公开(公告)号：US20170273904A1

公开(公告)日：2017-09-28

申请号：US15467778

申请日：2017-03-23

申请人： Industry-University Cooperation Foundation Hanyang University

发明人： Yong-Hee KIM ,  Jang-Kyung KIM ,  Jae Ho KOH

IPC分类号： A61K9/107 ,  A61K31/337 ,  A61K9/00 ,  A61K47/38

CPC分类号： A61K9/1075 ,  A61K9/0019 ,  A61K31/337 ,  A61K47/38

摘要： The present invention relates to a parenteral bioactive substance delivery composition and a bioactive substance carrier using a micelle based on low molecular weight methyl cellulose with a weight average molecular weight of 6 to 9.5 kDa. The bioactive substance carrier according to the present invention can completely resolve a problem of excretion to outside the body which cannot be resolved by conventional low molecular weight methyl cellulose having a weight average molecular weight of 10 to 20 kDa to increase safety and form a micelle to enable the solubilization of poorly soluble drugs, and thus is expected to be very useful for sustained release parenteral drug delivery.