专利检索 ap:("InhibRx. Inc.") AND inv:"Kyle JONES" 第 1 页

1.

发明公开
NON-PLATELET DEPLETING AND NON-RED BLOOD CELL DEPLETING CD47 ANTIBODIES AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20240166744A1

公开(公告)日：2024-05-23

申请号：US18451025

申请日：2023-08-16

申请人： InhibRx. Inc.

发明人： Brendan ECKELMAN , John Timmer , Amir Razai , Quinn DEVERAUX , Kyle JONES , Mark Lappe

IPC分类号： C07K16/28 , A61K39/395 , A61K45/06 , C07K14/705 , C07K16/30

CPC分类号： C07K16/2803 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K14/70503 , C07K16/30 , A61K2039/505 , C07K2319/21

摘要： This invention relates generally to monoclonal antibodies that recognize CD47, more specifically to CD47 antibodies that do not cause a significant level of agglutination of cells, red blood cell depletion, anemia, and/or platelet depletion, to methods of generating these antibodies, and to methods of using these monoclonal antibodies as therapeutics.