公开(公告)号：US20240412361A1

公开(公告)日：2024-12-12

申请号：US18746658

申请日：2024-06-18

Applicant: Insitro, Inc.

Inventor： Matthew Chen ,  Lauren Schiff ,  Alicia Cuevas ,  Kelly Haston ,  Haoyang Zeng ,  Cody Scandore

IPC: G06T7/00 ,  G06V10/82 ,  G06V20/69

Abstract: Embodiments of the disclosure include methods for implementing a predictive model that predicts pluripotency of cells through a cost efficient and non-destructive means. The predictive model analyzes contrast images captured from the cells and outputs predictions of cellular pluripotency at the cellular level. Thus, implementation of the predictive model guides the selection and isolation of cells that are predicted to be pluripotent. Furthermore, the predictive model facilitates retrospective analyses to correlate pluripotency metrics with differentiation success and further enables tracking of cellular pluripotency over time (e.g., to evaluate differentiation of cells).

公开(公告)号：US12045982B2

公开(公告)日：2024-07-23

申请号：US18233275

申请日：2023-08-11

Applicant: Insitro, Inc.

Inventor： Matthew Chen ,  Lauren Schiff ,  Alicia Cuevas ,  Kelly Haston ,  Haoyang Zeng ,  Cody Scandore

IPC: G06T7/00 ,  G06V10/82 ,  G06V20/69

CPC classification number: G06T7/0012 ,  G06V10/82 ,  G06V20/695 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/20084 ,  G06T2207/30072 ,  G06V2201/04

Abstract: Embodiments of the disclosure include methods for implementing a predictive model that predicts pluripotency of cells through a cost efficient and non-destructive means. The predictive model analyzes contrast images captured from the cells and outputs predictions of cellular pluripotency at the cellular level. Thus, implementation of the predictive model guides the selection and isolation of cells that are predicted to be pluripotent. Furthermore, the predictive model facilitates retrospective analyses to correlate pluripotency metrics with differentiation success and further enables tracking of cellular pluripotency over time (e.g., to evaluate differentiation of cells).

公开(公告)号：US20230401704A1

公开(公告)日：2023-12-14

申请号：US18233275

申请日：2023-08-11

Applicant: Insitro, Inc.

Inventor： Matthew Chen ,  Lauren Schiff ,  Alicia Cuevas ,  Kelly Haston ,  Haoyang Zeng ,  Cody Scandore

IPC: G06T7/00 ,  G16B20/00 ,  G06V20/69 ,  G06V10/82

CPC classification number: G06T7/0012 ,  G16B20/00 ,  G06V20/695 ,  G06V10/82 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30072 ,  G06V2201/04 ,  G06T2207/20084

Abstract: Embodiments of the disclosure include methods for implementing a predictive model that predicts pluripotency of cells through a cost efficient and non-destructive means. The predictive model analyzes contrast images captured from the cells and outputs predictions of cellular pluripotency at the cellular level. Thus, implementation of the predictive model guides the selection and isolation of cells that are predicted to be pluripotent. Furthermore, the predictive model facilitates retrospective analyses to correlate pluripotency metrics with differentiation success and further enables tracking of cellular pluripotency over time (e.g., to evaluate differentiation of cells).