Method for preparing tricarbonyl technetium-99m intermediate

    公开(公告)号:US10968245B2

    公开(公告)日:2021-04-06

    申请号:US16464919

    申请日:2016-12-28

    IPC分类号: A61K51/00 A61M36/14 C07F17/00

    摘要: The invention provides a method for preparing a technetium-99m tricarbonyl intermediate. The method comprises reacting a manganese carbonyl compound used as a carbon monoxide source with pertechnetate and water to obtain the technetium-99m tricarbonyl intermediate. The method for preparing a technetium-99m tricarbonyl intermediate in an embodiment of the invention can complete the preparation of the intermediate at atmospheric pressure and room temperature. The method is easy to operate, uses easily obtained raw materials, has a high labeling yield, and can be used to prepare various types of technetium tricarbonyl labeled probes.

    METHOD FOR PREPARING TRICARBONYL TECHNETIUM-99M INTERMEDIATE

    公开(公告)号:US20200010496A1

    公开(公告)日:2020-01-09

    申请号:US16464919

    申请日:2016-12-28

    IPC分类号: C07F17/00

    摘要: The invention provides a method for preparing a technetium-99m tricarbonyl intermediate. The method comprises reacting a manganese carbonyl compound used as a carbon monoxide source with pertechnetate and water to obtain the technetium-99m tricarbonyl intermediate. The method for preparing a technetium-99m tricarbonyl intermediate in an embodiment of the invention can complete the preparation of the intermediate at atmospheric pressure and room temperature. The method is easy to operate, uses easily obtained raw materials, has a high labeling yield, and can be used to prepare various types of technetium tricarbonyl labeled probes.