公开(公告)号：US20170258710A1

公开(公告)日：2017-09-14

申请号：US15067309

申请日：2016-03-11

Applicant: Intelgenx Corp.

Inventor： Justin Conway ,  Rodolphe Obeid ,  Nadine Paiement ,  Horst Zerbe

IPC: A61K9/00 ,  A61K47/36 ,  A61K9/70 ,  A61K31/47

CPC classification number: A61K9/006 ,  A61K9/146 ,  A61K9/7007 ,  A61K31/47 ,  A61K47/32 ,  A61K47/36

Abstract: An oral film product in which a pharmaceutically active agent is stabilized in its partially-ionized form to better facilitate oral transmucosal delivery is provided. The film includes a bioadhesive layer including a pharmaceutically active agent having a logarithmic acid dissociation constant that is less than 4.5 and which is complexed with a cationic polymer.