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    METHODS AND COMPOSITIONS FOR DETERMINING WHETHER A SUBJECT CARRIES A DISEASE ASSOCIATED GENE MUTATION COMMON IN JEWISH POPULATIONS
    1.
    发明申请
    METHODS AND COMPOSITIONS FOR DETERMINING WHETHER A SUBJECT CARRIES A DISEASE ASSOCIATED GENE MUTATION COMMON IN JEWISH POPULATIONS 审中-公开
    方法和组合物，用于确定一个主体是否在犹太人群体中相关疾病相关的基因突变共同

    公开(公告)号：US20100304985A1

    公开(公告)日：2010-12-02

    申请号：US11916439

    申请日：2007-10-25

    申请人： Iris Schrijver ,  Phyllis Gardner ,  Eugene Pergament ,  Morry Fiddler

    发明人： Iris Schrijver ,  Phyllis Gardner ,  Eugene Pergament ,  Morry Fiddler

    IPC分类号： C40B30/04 ,  C40B40/06

    CPC分类号： C12Q1/6883 ,  C12Q2600/156

    摘要： Methods are provided for determining whether a subject carries a disease associated gene mutation common in Jewish populations. In practicing the subject methods, an array comprising a plurality of associated gene mutation probes is contacted with a nucleic acid sample from the subject, and the presence of any resultant surface bound target nucleic acids is detected to determine whether the subject carries an disease associated gene mutation common in Jewish populations. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.

    摘要翻译： 提供方法用于确定受试者是否携带犹太人口中常见的疾病相关基因突变。 在实施本发明方法时，将包含多个相关基因突变探针的阵列与来自受试者的核酸样品接触，并检测任何所得表面结合靶核酸的存在，以确定受试者是否携带疾病相关基因 在犹太人群中常见的突变。 此外，提供了用于实践本发明方法的试剂和试剂盒。

    Methods and compositions for determining whether a subject carries a cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation
    2.
    发明申请
    Methods and compositions for determining whether a subject carries a cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation 审中-公开
    用于确定受试者是否携带囊性纤维化跨膜传导调节因子（CFTR）基因突变的方法和组合物

    公开(公告)号：US20050048544A1

    公开(公告)日：2005-03-03

    申请号：US10888435

    申请日：2004-07-09

    申请人： Phyllis Gardner ,  Iris Schrijver

    发明人： Phyllis Gardner ,  Iris Schrijver

    IPC分类号： A61B20060101 ,  C12P19/34 ,  C12Q1/68

    CPC分类号： C12Q1/6883 ,  C12Q2600/156

    摘要： Methods are provided for determining whether a subject carries a CFTR gene mutation. In practicing the subject methods, an array comprising a plurality of CFTR gene mutation probes is contacted with a nucleic acid sample from the subject, and the presence of any resultant surface bound target nucleic acids is detected to determine whether the subject carries a CFTR gene mutation. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.

    摘要翻译： 提供了确定受试者是否携带CFTR基因突变的方法。 在实施本发明方法时，将包含多个CFTR基因突变探针的阵列与来自受试者的核酸样品接触，并检测任何所得表面结合靶核酸的存在，以确定受试者是否携带CFTR基因突变 。 此外，提供了用于实践本发明方法的试剂和试剂盒。