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    Hormone replacement therapy method
    1.
    发明授权
    Hormone replacement therapy method 失效

    公开(公告)号：US06551611B2

    公开(公告)日：2003-04-22

    申请号：US09562316

    申请日：2000-05-01

    申请人： Jörg Elliesen ,  Jutta Riedl

    发明人： Jörg Elliesen ,  Jutta Riedl

    IPC分类号： A61F1300

    CPC分类号： B65D83/0011 ,  A61K9/06 ,  A61K31/565 ,  A61K31/57 ,  B65D35/22 ,  B65D81/325 ,  B65D83/0005 ,  A61K2300/00

    摘要： Varying the daily dose of either or both of the estrogen and the progestogen administered for hormone replacement therapy (HRT) is readily and inexpensively accomplished, without the necessity of the physician prescribing a new product each time the daily dose of the estrogen or progestogen is changed, by administering preferably transdermally the estrogen and the progestogen contained in separate extrudable pharmaceutical compositions from a dispenser which contains means, preferably adjustable only by the attending physician or dispensing pharmacist, for varying the volume of either or both of the respective compositions which is dispensed as a single dose from the dispenser in response to a defined digital dispensing manipulation of the dispenser thereby facilitating optimal compliance to a combination of HRT with individually adjusted dosages of the estrogen and progestogen.

    Hormone replacement therapy method and hormone dispenser
    4.
    发明授权
    Hormone replacement therapy method and hormone dispenser 失效
    激素替代治疗方法和激素分配器

    公开(公告)号：US6083528A

    公开(公告)日：2000-07-04

    申请号：US288225

    申请日：1999-04-08

    申请人： Jorg Elliesen ,  Jutta Riedl

    发明人： Jorg Elliesen ,  Jutta Riedl

    IPC分类号： A61K31/57 ,  A61F13/00

    CPC分类号： A61K31/57

    摘要： Varying the daily dose of either or both of the estrogen and the progestogen administered for hormone replacement therapy (HRT) is readily and inexpensively accomplished, without the necessity of the physician prescribing a new product each time the daily dose of the estrogen or progestogen is changed, by administering preferably transdermally the estrogen and the progestogen contained in separate extrudable pharmaceutical compositions from a dispenser which contains means, preferably adjustable only by the attending physician or dispensing pharmacist, for varying the volume of either or both of the respective compositions which is dispensed as a single dose from the dispenser in response to a defined digital dispensing manipulation of the dispenser thereby facilitating optimal compliance to a combination of HRT with individually adjusted dosages of the estrogen and progestogen.

    摘要翻译： 雌激素和孕激素替代疗法（HRT）中的一种或两种雌激素和孕激素的日剂量随着雌激素或孕激素每日剂量的变化而变化，不需要医生处方新产品 通过优选经皮内施用包含在来自分配器的分开的可挤出药物组合物中的雌激素和孕激素，其包含优选仅由主治医师或分配药剂师调节以改变分配为相应组合物中的任一个或两者的体积的装置 响应于分配器的定义的数字分配操作，来自分配器的单次剂量，从而促进最佳顺应HRT与雌激素和孕激素的单独调整剂量的组合。