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公开(公告)号：US20180104263A1
公开(公告)日：2018-04-19
申请号：US15699944
申请日：2017-09-08
发明人： Roger A. Acey , Kensaku Nakayama
IPC分类号： A61K31/6615 , C07F9/24 , C07F9/18 , A61K9/00 , C07F9/12
CPC分类号： A61K31/6615 , A61K9/0019 , C07F9/12 , C07F9/18 , C07F9/242
摘要： Butyrylcholinesterase inhibitors, their formulation, and their use primarily in the treatment of neurodegenerative diseases. These inhibitors generally are phosphates, phosphonates, phosphinates, and phosphoramidates.These inhibitors can be incorporated in pharmaceutical compositions and administered to a patient in therapeutically effective amounts to treat neurodegenerative diseases.
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公开(公告)号：US09757399B2
公开(公告)日：2017-09-12
申请号：US15004797
申请日：2016-01-22
发明人： Roger A. Acey , Kensaku Nakayama
IPC分类号： A61K31/661 , A61K31/6615 , A61K9/00 , C07F9/12 , C07F9/18 , C07F9/24
CPC分类号： A61K31/6615 , A61K9/0019 , C07F9/12 , C07F9/18 , C07F9/242
摘要： Butyrylcholinesterase inhibitors, their formulation, and their use primarily in the treatment of neurodegenerative diseases. These inhibitors generally are phosphates, phosphonates, phosphinates, and phosphoramidates.These inhibitors can be incorporated in pharmaceutical compositions and administered to a patient in therapeutically effective amounts to treat neurodegenerative diseases.
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公开(公告)号：US20160206635A1
公开(公告)日：2016-07-21
申请号：US15004797
申请日：2016-01-22
发明人： Roger A. Acey , Kensaku Nakayama
IPC分类号： A61K31/6615 , A61K9/00
CPC分类号： A61K31/6615 , A61K9/0019 , C07F9/12 , C07F9/18 , C07F9/242
摘要： Butyrylcholinesterase inhibitors, their formulation, and their use primarily in the treatment of neurodegenerative diseases. These inhibitors generally are phosphates, phosphonates, phosphinates, and phosphoramidates.These inhibitors can be incorporated in pharmaceutical compositions and administered to a patient in therapeutically effective amounts to treat neurodegenerative diseases.
摘要翻译： 丁酰胆碱酯酶抑制剂，其制剂及其用途主要用于治疗神经变性疾病。 这些抑制剂通常是磷酸盐，膦酸盐，次膦酸盐和氨基磷酸酯。 这些抑制剂可并入药物组合物中，并以治疗有效量施用于患者以治疗神经变性疾病。
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