公开(公告)号：US20170176430A1

公开(公告)日：2017-06-22

申请号：US15321312

申请日：2015-07-01

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroyuki NOJI ,  Lisa YAMAUCHI

IPC: G01N33/543 ,  G01N21/64 ,  G01N33/53

CPC classification number: G01N33/54393 ,  C12Q1/04 ,  C12Q1/68 ,  C12Q1/70 ,  G01N21/6428 ,  G01N33/5308 ,  G01N33/543 ,  G01N33/54313 ,  G01N35/10 ,  G01N37/00 ,  G01N2021/6439

Abstract: As a technique for efficiently sealing many substances, such as beads, nucleic acid, protein, virus, cells, and lipid membrane complex, into an array, the present invention provides a method for sealing a substance, including: (i) a step of introducing a first solvent containing a substance on a substrate on which a plurality of receptacles capable of storing the substance are formed separated from each other by a side wall; and (ii) a step of introducing a second solvent having a greater specific gravity than that of the first solvent onto the first solvent, the step (ii) being carried out after the step (i).

公开(公告)号：US20150087547A1

公开(公告)日：2015-03-26

申请号：US14513660

申请日：2014-10-14

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroyuki NOJI ,  Lisa YAMAUCHI

IPC: G01N21/64

CPC classification number: G01N33/54313 ,  G01N33/54393

Abstract: [Problem to be Solved]A technique for efficiently sealing many substances, such as beads, nucleic acid, protein, virus, cells, and lipid membrane complex, into an array is provided.[Solution]The present invention provides a method for sealing a substance, including: (i) a step of introducing a first solvent containing a substance on a substrate on which a plurality of receptacles capable of storing the substance are formed separated from each other by a side wall; and (ii) a step of introducing a second solvent having a greater specific gravity than that of the first solvent onto the first solvent, the step (ii) being carried out after the step (i).

Abstract translation: [待解决的问题]提供了将许多物质如珠，核酸，蛋白质，病毒，细胞和脂质膜复合物有效密封成阵列的技术。 本发明提供一种密封物质的方法，包括：（i）将含有物质的第一溶剂引入到其上形成有能够存储物质的多个容器彼此分离的基底上的步骤， 侧墙 和（ii）将比重大于第一溶剂的第二溶剂的第二溶剂引入第一溶剂的步骤，步骤（ii）在步骤（i）之后进行。