公开(公告)号：US09802907B2

公开(公告)日：2017-10-31

申请号：US14648664

申请日：2013-11-24

申请人： JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD.

发明人： Dongfang Shi ,  Changjin Fu ,  Jie Wu ,  Jun Liu

IPC分类号： C07D293/06 ,  C07D421/10 ,  A61K31/381 ,  A61K33/04 ,  A61K31/41 ,  A61K31/4365 ,  A61K31/4439 ,  A61K31/496 ,  A61K31/5377 ,  C07D421/12 ,  C07D495/04

CPC分类号： C07D293/06 ,  A61K31/41 ,  A61K31/4365 ,  A61K31/4439 ,  A61K31/496 ,  A61K31/5377 ,  C07D421/10 ,  C07D421/12 ,  C07D495/04

摘要： A 2-aryl selenazole compound and a pharmaceutical composition are disclosed, wherein the 2-aryl selenazole compound is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The 2-aryl selenazole compound has the activity of inhibiting xanthine oxidase. The compound or a pharmaceutically acceptable salt thereof can be applied in terms of preparing a drug used for prevention or treatment of hyperuricemia, gout, diabetic nephropathy, an inflammatory disease or a neurological disease.