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公开(公告)号：US20120089082A1
公开(公告)日：2012-04-12
申请号：US13332226
申请日：2011-12-20
IPC分类号： A61M37/00
CPC分类号： A61M5/14 , A61B1/00135 , A61B8/12 , A61B17/22 , A61B17/2202 , A61B17/320068 , A61B2017/22082 , A61B2017/22084 , A61B2017/320072 , A61B2017/320084 , A61B2018/00011 , A61M25/007 , A61M37/0092 , A61M2025/0057 , A61M2025/105
摘要： An apparatus for delivering ultrasound energy and a drug solution to a treatment site in a vessel is disclosed. The apparatus includes an elongate, hollow sheath having a distal opening and an energy delivery section at least partially constructed from a material that transmits ultrasound energy. The apparatus also includes a drug delivery lumen positioned along at least a portion of the sheath, the drug delivery lumen having at least one drug delivery port within the energy delivery section. The apparatus further includes an elongate body having an ultrasound element, the elongate body configured to be movably positioned within the sheath, such that ultrasonic energy can be transmitted from the ultrasound element through the energy delivery section.
摘要翻译： 公开了一种用于将超声能量和药物溶液输送到容器中的治疗部位的装置。 该装置包括细长的中空护套，其具有远端开口和至少部分地由透射超声能量的材料构成的能量传递部分。 该装置还包括沿护套的至少一部分定位的药物递送腔，药物递送腔具有在能量输送部分内的至少一个药物递送端口。 该装置还包括具有超声波元件的细长主体，细长主体被配置为可移动地定位在护套内，使得超声能量可以从超声波元件通过能量输送部分传递。
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公开(公告)号：US20090105633A1
公开(公告)日：2009-04-23
申请号：US12252291
申请日：2008-10-15
CPC分类号： A61M37/0092 , A61B17/2202 , A61B2017/22062 , A61B2017/22088 , A61K41/0047
摘要： A kit and method for causing tissue death within a tissue site is disclosed. The kit includes a media with a light activated drug activatable upon exposure to a particular level of ultrasound energy. The kit also includes an ultrasound transducer that is configured to transmit the level of ultrasound energy which activates the light activated drug with sufficient power that the ultrasound energy can penetrate the tissue site. The method includes providing the media comprising a light activated drug, delivering the media systematically into a patient's body, providing sufficient time for the light activated drug to localize within the tissue site, and directing ultrasound energy to the light activated drug within the tissue site to thereby activate the light activated drug.
摘要翻译： 公开了一种用于在组织部位内引起组织死亡的试剂盒和方法。 该试剂盒包括在暴露于特定水平的超声能量时可激活的具有光活化药物的培养基。 该套件还包括超声换能器，其被配置为传输超声能量的水平，其以足够的功率激活光活化药物，超声能量可以穿透组织部位。 该方法包括提供包含轻活化药物的介质，将系统性地将介质输送到患者体内，为光活化药物定位在组织部位内提供足够的时间，以及将超声能量引导至组织部位内的光活化药物至 从而激活光活化药物。
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