利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

2 条记录 (耗时 0.014 秒)

    PROCESS FOR SCREENING OF A BINDING AMPHIPHILIC PEPTIDES SPECIFIC FOR HAIRPIN RNA
    1.
    发明申请
    PROCESS FOR SCREENING OF A BINDING AMPHIPHILIC PEPTIDES SPECIFIC FOR HAIRPIN RNA 有权
    用于筛选特定于头发RNA的结合蛋白肽的方法

    公开(公告)号：US20100173796A1

    公开(公告)日：2010-07-08

    申请号：US12540246

    申请日：2009-08-12

    申请人： Jaehoon YU ,  Jeffrey Kieft ,  Su Jin Lee

    发明人： Jaehoon YU ,  Jeffrey Kieft ,  Su Jin Lee

    IPC分类号： C40B30/04 ,  C40B40/10

    CPC分类号： C07K7/08

    摘要： The present invention relates to a screening method of an amphiphilic peptide specifically binding to hairpin RNA, more precisely a screening method of an amphiphilic peptide having specificity and strong binding strength to target hairpin RNA using peptide library comprising those peptides having modifications of both hydrophilic face and hydrophobic face. The method of the present invention provides a screening method of an amphiphilic peptide which is specific to hairpin RNA. So, the peptide selected by the method of the present invention can be effectively used for the study of hairpin RNA functions and for the production of a novel drug using an artificial peptide binding to a hairpin RNA target.

    摘要翻译： 本发明涉及特异性结合发夹RNA的两亲性肽的筛选方法，更确切地说，使用肽文库的具有特异性和对靶发夹RNA的强结合强度的两亲肽的筛选方法，所述肽文库包括具有亲水性面部和 疏水面。 本发明的方法提供了对发夹RNA特异性的两亲肽的筛选方法。 因此，通过本发明的方法选择的肽可以有效地用于研究发夹RNA功能，并且可以使用结合发夹RNA靶的人工肽来生产新药。

    PROCESS FOR SCREENING OF A BINDING PEPTIDE SPECIFIC FOR SPECIFIC RNA AND RNA BINDING PEPTIDES THEREFROM
    2.
    发明申请
    PROCESS FOR SCREENING OF A BINDING PEPTIDE SPECIFIC FOR SPECIFIC RNA AND RNA BINDING PEPTIDES THEREFROM 有权
    用于特异性RNA和RNA结合肽结合肽特异性筛选的方法

    公开(公告)号：US20080318797A1

    公开(公告)日：2008-12-25

    申请号：US11457773

    申请日：2006-07-14

    申请人： Jaehoon YU

    发明人： Jaehoon YU

    IPC分类号： C40B30/04 ,  C40B40/10

    CPC分类号： C07K7/08 ,  G01N2500/04

    摘要： The present invention relates to a screening method for RNA specific binding peptide using alpha-helical peptides. The screening method for RNA specific binding peptide of the present invention using alpha-helical peptides enables the selection of a peptide having strong binding capacity to a specific RNA having particular morphology and nucleotide sequence and the investigation of functions of RNA using the selected peptides, and is very useful for the production of a new drug using synthetic peptide having more powerful and specific binding capacity to RNA than those of natural peptides.

    摘要翻译： 本发明涉及使用α-螺旋肽的RNA特异性结合肽的筛选方法。 使用α-螺旋肽的本发明的RNA特异性结合肽的筛选方法使得能够选择对具有特定形态和核苷酸序列的特异性RNA具有强结合能力的肽，以及使用所选择的肽对RNA功能的研究，以及 对于使用具有比天然肽更强大和特异的RNA结合能力的合成肽来生产新药物是非常有用的。