Multi-layer delivery system
    1.
    发明授权
    Multi-layer delivery system 失效
    多层交付系统

    公开(公告)号:US4957494A

    公开(公告)日:1990-09-18

    申请号:US283631

    申请日:1988-12-13

    IPC分类号: A61K9/00 A61M31/00

    CPC分类号: A61M31/002 A61K9/0004

    摘要: A dispenser for use in a fluid environment which is capable of delivery of plurality of discrete drug containing layers in any desired delivery pattern or profile. The dispenser comprises a rigid housing containing a plurality of drug layers which may be separated by drug-free layers. An outlet is provided at one end of the housing and a fluid actuated driving means is provided between the other end of the housing and the drug layers. The portion of the housing in proximity to the driving means has a controlled permeability to water whereby, upon immersion in a fluid environment the drug layers are driven towards the outlet. Various delivery patterns are possible by appropriate selection of the comparison and dimensions of the drug and drug-free layers.

    摘要翻译: 一种在流体环境中使用的分配器,其能够以任何期望的输送模式或轮廓递送多个离散的含药层。 分配器包括容纳多个药物层的刚性壳体,其可由无药物层分离。 出口设在壳体的一端,并且流体驱动的驱动装置设置在壳体的另一端和药物层之间。 壳体靠近驱动装置的部分对水具有受控的渗透性,因此当浸入流体环境中时,药物层朝着出口被驱动。 可以通过适当选择药物和无药物层的比较和尺寸来实现各种递送模式。

    Dispenser with movable matrix comprising a plurality of tiny pills
    2.
    发明授权
    Dispenser with movable matrix comprising a plurality of tiny pills 失效
    具有可移动矩阵的分配器,包括多个微小的药丸

    公开(公告)号:US4915949A

    公开(公告)日:1990-04-10

    申请号:US312270

    申请日:1989-02-21

    IPC分类号: A61K9/00 A61K9/22

    CPC分类号: A61K9/0068 A61K9/0004

    摘要: A dispenser is disclosed for delivering tiny pills to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, tiny pills in the first means, and a second means in the dispenser for aiding in displacing the first means for the dispenser.

    摘要翻译: 公开了用于将微小丸剂递送到使用环境的分配器。 所述分配器包括围绕内部空间的壁,所述壁包括所述分配器中的第一平均值,用于在离开所述分配器时从分配器状态改变为使用状态,所述第一装置中的小丸和用于辅助的所述分配器中的第二装置 在移动分配器的第一装置时。

    Multi-layer delivery system
    5.
    发明授权
    Multi-layer delivery system 失效
    多层交付系统

    公开(公告)号:US4874388A

    公开(公告)日:1989-10-17

    申请号:US66906

    申请日:1987-06-25

    CPC分类号: A61M31/002 A61K9/0004

    摘要: A dispenser for use in a fluid environment having a rigid housing containing a fluid activated driving member, a plurality of drug containing layers and an outlet means by which drug is dispensed to the environment. The housing adjacent to the layers is fluid impermeable and the housing adjacent to the driving member is fluid permeable or has an open area by which fluid can contact the driving member. O048743884

    摘要翻译: 一种在流体环境中使用的分配器,其具有容纳流体激活的驱动构件,多个药物容纳层的刚性壳体和药物分配到环境中的出口装置。 与层相邻的壳体是流体不可渗透的,并且与驱动构件相邻的壳体是流体可渗透的或具有开口区域,流体可以通过该开口区域接触驱动构件。 O048743884