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    SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR PREVENTING RETINAL DYSFUNCTION
    5.
    发明申请
    SUSTAINED RELEASE INTRAOCULAR IMPLANTS AND METHODS FOR PREVENTING RETINAL DYSFUNCTION 有权
    可持续释放内镜植入物和预防后遗症的方法

    公开(公告)号：US20080131372A1

    公开(公告)日：2008-06-05

    申请号：US11927615

    申请日：2007-10-29

    申请人： Glenn T. Huang ,  James Burke ,  Patrick M. Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry A. Wheeler ,  Rosy Sheng Donn

    发明人： Glenn T. Huang ,  James Burke ,  Patrick M. Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry A. Wheeler ,  Rosy Sheng Donn

    IPC分类号： A61K31/498 ,  A61P27/16

    CPC分类号： A61K31/498 ,  A61K9/0051 ,  A61K47/34

    摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to prevent the occurrence of one or more ocular conditions, or to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like.

    摘要翻译： 生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。 植入物可以放置在眼睛中以防止发生一种或多种眼部病症，或者减少眼部疾病如眼睛神经感觉障碍等的一种或多种症状。

    Sustained release intraocular implants and methods for preventing retinal dysfunction
    6.
    发明授权
    Sustained release intraocular implants and methods for preventing retinal dysfunction 有权
    持续释放眼内植入物和预防视网膜功能障碍的方法

    公开(公告)号：US08293210B2

    公开(公告)日：2012-10-23

    申请号：US11927615

    申请日：2007-10-29

    申请人： Glenn T. Huang ,  James Burke ,  Patrick M. Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry A. Wheeler ,  Rosy Sheng Donn

    发明人： Glenn T. Huang ,  James Burke ,  Patrick M. Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry A. Wheeler ,  Rosy Sheng Donn

    IPC分类号： A61K31/498 ,  A61P27/16

    CPC分类号： A61K31/498 ,  A61K9/0051 ,  A61K47/34

    摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to prevent the occurrence of one or more ocular conditions, or to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like.

    摘要翻译： 生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。 植入物可以放置在眼睛中以防止发生一种或多种眼部病症，或者减少眼部疾病如眼睛神经感觉障碍等的一种或多种症状。

    Sustained release intraocular implants and methods for preventing retinal dysfunction
    7.
    发明申请
    Sustained release intraocular implants and methods for preventing retinal dysfunction 审中-公开
    持续释放眼内植入物和预防视网膜功能障碍的方法

    公开(公告)号：US20110251201A1

    公开(公告)日：2011-10-13

    申请号：US13154079

    申请日：2011-06-06

    申请人： Glenn T. Huang ,  James Burke ,  Patrick M. Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry A. Wheeler ,  Rosy Sheng Donn

    发明人： Glenn T. Huang ,  James Burke ,  Patrick M. Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry A. Wheeler ,  Rosy Sheng Donn

    IPC分类号： A61K31/498 ,  A61P27/02

    CPC分类号： A61K31/498 ,  A61K9/0051 ,  A61K47/34

    摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to prevent the occurrence of one or more ocular conditions, or to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like.

    摘要翻译： 生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。 植入物可以放置在眼睛中以防止发生一种或多种眼部病症，或者减少眼部疾病如眼睛神经感觉障碍等的一种或多种症状。

    Sustained release intraocular implants and methods for preventing retinal dysfunction
    9.
    发明申请
    Sustained release intraocular implants and methods for preventing retinal dysfunction 审中-公开
    持续释放眼内植入物和预防视网膜功能障碍的方法

    公开(公告)号：US20050244506A1

    公开(公告)日：2005-11-03

    申请号：US11118519

    申请日：2005-04-29

    申请人： James Burke ,  Patrick Hughes ,  Werhner Orilla ,  Ton Lin ,  Maria Escobar ,  Glenn Huang ,  Kai-Ming Zhang ,  Larry Wheeler ,  Rosy Donn

    发明人： James Burke ,  Patrick Hughes ,  Werhner Orilla ,  Ton Lin ,  Maria Escobar ,  Glenn Huang ,  Kai-Ming Zhang ,  Larry Wheeler ,  Rosy Donn

    IPC分类号： A61F2/02 ,  A61K9/00 ,  A61K9/14 ,  A61K31/498

    CPC分类号： A61K31/498 ,  A61K9/0051 ,  A61K47/34

    摘要： Biocompatible intraocular microspheres and implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or to prevent the occurrence of one or more ocular conditions, to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like, to enhance normal retinal function and/or to lower intraocular pressure.

    摘要翻译： 生物相容的眼内微球和植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。 植入物可以放置在眼睛中以治疗或防止一种或多种眼部病症的发生，以减少眼部疾病如眼部神经感觉障碍等的一种或多种症状，以增强正常的视网膜功能和/ 或降低眼内压。

    Sustained release intraocular implants and methods for preventing retinal dysfunction
    10.
    发明申请
    Sustained release intraocular implants and methods for preventing retinal dysfunction 有权
    持续释放眼内植入物和预防视网膜功能障碍的方法

    公开(公告)号：US20050244479A1

    公开(公告)日：2005-11-03

    申请号：US10837143

    申请日：2004-04-30

    申请人： Glenn Huang ,  James Burke ,  Patrick Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry Wheeler ,  Rosy Donn

    发明人： Glenn Huang ,  James Burke ,  Patrick Hughes ,  Kai-Ming Zhang ,  Ton Lin ,  Larry Wheeler ,  Rosy Donn

    IPC分类号： A61F2/02 ,  A61K9/00 ,  A61K9/14 ,  A61K31/498

    CPC分类号： A61K31/498 ,  A61K9/0051 ,  A61K47/34

    摘要： Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to prevent the occurrence of one or more ocular conditions, or to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like.

    摘要翻译： 生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。 植入物可以放置在眼睛中以防止发生一种或多种眼部病症，或者减少眼部疾病如眼睛神经感觉障碍等的一种或多种症状。