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1.发明申请METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS 审中-公开用于确定药物滥用药物产品的方法和组合物公开(公告)号：US20130005823A1
公开(公告)日：2013-01-03
申请号：US13601239
申请日：2012-08-31
IPC分类号： A61K31/137
CPC分类号： A61K9/0043 , A61K9/146 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2031 , A61K9/205 , A61K9/2054 , A61K9/2059 , A61K9/2095 , A61K9/4808 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K9/5078 , A61K9/5084 , A61K31/74 , A61K45/06 , A61K2300/00
摘要： This invention relates to an abuse deterrent formulation of an oral dosage form of a therapeutically effective amount of any active drug substance that can be subject to abuse combined with a gel forming polymer, a nasal mucosal irritating surfactant and a flushing agent. Such a dosage form is intended to deter abuse of the active drug substance via injection, nasal inhalation or consumption of quantities of the dosage unit exceeding the usual therapeutically effective dose.
摘要翻译： 本发明涉及治疗有效量的任何活性药物的口服剂型的滥用威慑制剂，其可与凝胶形成聚合物，鼻粘膜刺激性表面活性剂和冲洗剂混合使用。 这种剂型旨在通过注射，鼻吸入或消耗超过通常治疗有效剂量的剂量单位的量来阻止活性药物物质的滥用。
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2.发明申请METHODS AND COMPOSITIONS FOR DETERRING ABUSE OF ORALLY ADMINISTERED PHARMACEUTICAL PRODUCTS 审中-公开用于确定药物滥用药物产品的方法和组合物公开(公告)号：US20120202839A1
公开(公告)日：2012-08-09
申请号：US13450102
申请日：2012-04-18
IPC分类号： A61K31/485 , A61P25/04 , A61K47/36
CPC分类号： A61K9/0043 , A61K9/146 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2013 , A61K9/2027 , A61K9/2031 , A61K9/205 , A61K9/2054 , A61K9/2059 , A61K9/2095 , A61K9/4808 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K9/5026 , A61K9/5078 , A61K9/5084 , A61K31/74 , A61K45/06 , A61K2300/00
摘要： This invention relates to an abuse deterrent formulation of an oral dosage form of a therapeutically effective amount of any active drug substance that can be subject to abuse combined with a gel forming polymer, a nasal mucosal irritating surfactant and a flushing agent. Such a dosage form is intended to deter abuse of the active drug substance via injection, nasal inhalation or consumption of quantities of the dosage unit exceeding the usual therapeutically effective dose.
摘要翻译： 本发明涉及治疗有效量的任何活性药物的口服剂型的滥用威慑制剂，其可与凝胶形成聚合物，鼻粘膜刺激性表面活性剂和冲洗剂混合使用。 这种剂型旨在通过注射，鼻吸入或消耗超过通常治疗有效剂量的剂量单位的量来阻止活性药物物质的滥用。
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