公开(公告)号：US20240141032A1

公开(公告)日：2024-05-02

申请号：US17974956

申请日：2022-10-27

Applicant: Janssen Biotech, Inc.

Inventor： Matthew Germinaro ,  Mobolaji Olurinde ,  Aparna Sahoo ,  Jacqueline Yee ,  Omoniyi Adedokun

IPC: C07K16/24 ,  A61P37/02

CPC classification number: C07K16/244 ,  A61P37/02 ,  A61K2039/505

Abstract: A method of treating Crohn's disease in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial subcutaneous dose and subsequent subcutaneous doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.