公开(公告)号：US20170360606A1

公开(公告)日：2017-12-21

申请号：US15609457

申请日：2017-05-31

Applicant: Janssen Biotech, Inc.

Inventor： Daniel W. Price ,  Brendan J. Oberkircher ,  James G. Lee ,  Clinton Denlinger ,  Daniel J. Prenger ,  Geoffrey King ,  Scott Uhland ,  Mark C. Tsai ,  Michael F. Keane ,  Isaac J. Khan ,  Benjamin L. Ko ,  Thomas E. Meyer ,  Denis P. Turner

IPC: A61F9/00

Abstract: An apparatus includes a pad assembly, an injector assembly, an injector driver, and a fluid source. The pad assembly is sized and configured to be placed on a forehead of a patient. The injector assembly includes a body, a flexible cannula, and a needle. The body is configured to be removably secured to the pad assembly. The cannula is sized to be inserted through an incision in an eye of a patient. The needle is slidably disposed in the cannula. The injector driver is operable to drive the needle longitudinally relative to the flexible cannula. The fluid source assembly is in fluid communication with the needle.

公开(公告)号：US09949874B2

公开(公告)日：2018-04-24

申请号：US14726786

申请日：2015-06-01

Applicant: Janssen Biotech, Inc.

Inventor： Joseph H. Contiliano ,  Thomas E. Meyer ,  Daniel J. Abbott ,  Michael F. Keane ,  Allen C. Ho ,  Mark C. Tsai ,  Isaac J. Khan

IPC: A61F9/00 ,  A61M25/06

CPC classification number: A61F9/0008 ,  A61F9/0017 ,  A61F9/0026 ,  A61M25/065 ,  A61M25/0662 ,  A61M2025/0681

Abstract: An apparatus has a first fluid conduit, a second fluid conduit, a connector member, an first tubular member, a second tubular member, and an inner cannula. The connector member has first and second passageways in which the first and second fluid conduits are positioned, respectively. A portion of the second tubular member is positioned within the lumen of the first tubular member. A proximal portion of the inner cannula is fixedly secured within the lumen of the first tubular member. The inner cannula lumen is in fluid communication with the first and second fluid conduits via the lumen of the first tubular member and the lumen of the second tubular member. The inner cannula may be inserted into the subretinal space of a human eye to deliver a leading bleb of fluid and then deliver a therapeutic agent, without having to withdraw the inner cannula from the subretinal space between the acts of delivering the leading bleb delivering the therapeutic agent.

公开(公告)号：US20170258988A1

公开(公告)日：2017-09-14

申请号：US15438918

申请日：2017-02-22

Applicant: Janssen Biotech, Inc.

Inventor： Thomas E. Meyer ,  Benjamin L. Ko ,  Isaac J. Khan ,  Daniel W. Price ,  Brendan J. Oberkircher ,  Michael F. Keane

IPC: A61M5/158 ,  A61F9/00 ,  A61M5/168

CPC classification number: A61M5/158 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/0026 ,  A61M5/168 ,  A61M5/329 ,  A61M2005/1585 ,  A61M2205/582 ,  A61M2210/0612

Abstract: An apparatus includes a body, a cannula, and a needle. The cannula is flexible and extends distally from the body. The needle is slidably disposed in the cannula. The needle includes a sharp distal tip and a curved portion. The needle is configured to translate relative to the cannula between a proximal position and a distal position. The distal tip is configured to be positioned inside the cannula when the needle is in the proximal position. The distal tip is configured to be positioned outside the cannula when the needle is in the distal position. The needle is resiliently biased to extend along a curve through the curved portion.

公开(公告)号：US20180200108A1

公开(公告)日：2018-07-19

申请号：US15865533

申请日：2018-01-09

Applicant: Janssen Biotech, Inc.

Inventor： Daniel W. Price ,  Brendan J. Oberkircher ,  Daniel J. Prenger ,  Geoffrey King ,  Isaac J. Khan ,  Michael F. Keane

IPC: A61F9/007 ,  A61F9/00

CPC classification number: A61F9/00736 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/00781 ,  A61M5/46 ,  A61M2210/0612

Abstract: An apparatus includes a body, a cannula, a conduit, and a magnetic element. The cannula extends distally from the body. The cannula is flexible and has a distal end. The cannula defines a lumen distally terminating at the distal end. The cannula is sized and configured to pass between a sclera layer and a choroid layer in a human eye. The conduit is in fluid communication with the lumen. The magnetic element is positioned in the body.

公开(公告)号：US20170360605A1

公开(公告)日：2017-12-21

申请号：US15609419

申请日：2017-05-31

Applicant: Janssen Biotech, Inc.

Inventor： Brendan J. Oberkircher ,  Benjamin L. Ko ,  Robert H. Roth ,  Mark S. Ortiz ,  Thomas E. Meyer ,  Franklin S. Busch ,  Isaac J. Khan ,  Michael F. Keane ,  Anna R. Raymond ,  Jacob W. Schubert

IPC: A61F9/00

CPC classification number: A61F9/0026 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/0136

Abstract: An apparatus includes a body and a pair of rigid legs extending from the body. The body includes an engagement feature configured to engage a deployment instrument. The legs are parallel with each other. Each leg has a sharp tip. The legs both extend along a plane. The body defines a guide opening. The guide opening is oriented transversely relative to the plane associated with the legs. The guide opening is sized to receive a cannula having a generally flat profile. The guide opening is configured to guide the cannula through a sclerotomy at a substantially tangential orientation.