公开(公告)号：US20180334492A1

公开(公告)日：2018-11-22

申请号：US16032691

申请日：2018-07-11

Applicant: Janssen Biotech, Inc.

Inventor： Steven Jacobs ,  Karyn O'neil

IPC: C07K14/78

CPC classification number: C07K14/78 ,  C40B40/08 ,  C40B50/06

Abstract: A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications.