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公开(公告)号:US20220112282A1
公开(公告)日:2022-04-14
申请号:US17496057
申请日:2021-10-07
Applicant: Janssen Biotech, Inc.
Inventor: Frederic Lavie , Manuela Le Bars , Michael Plotnick , Sheldon Sloan
Abstract: Methods and compositions for clinical proven safe and effective treatment of Crohn's disease, particularly moderately to severely active Crohn's disease in patients, comprise intravenous initial dosing and subcutaneous maintenance dosing of an anti-IL12/IL23p40 antibody with maintenance dose intervals determined by evaluating clinical indicators.