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公开(公告)号:US11548941B2
公开(公告)日:2023-01-10
申请号:US16688178
申请日:2019-11-19
Applicant: Janssen Biotech, Inc.
Inventor: Julianty Angsana , Patrick Branigan , Samuel DePrimo , Susan Flavin , Shu Li , Xuejun Liu , Ernesto Munoz , Bruce Randazzo
IPC: C07K16/24 , A61K39/395 , A61P17/06 , A61K45/06
Abstract: A method of treating psoriasis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves PASI90, PASI100 or IGA 0 or 1 score as measured 16, 24, 32, 40 and 48 weeks after initial treatment and the patient achieves higher efficacy than a patient treated with the secukinumab antibody.
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公开(公告)号:US20230312703A1
公开(公告)日:2023-10-05
申请号:US18128310
申请日:2023-03-30
Applicant: Janssen Biotech, Inc.
Inventor: Daphne Chan , Olivia Choi , Long-Long Gao , Jenny Jeyarajah , Shu Li , Katelyn Rowland , Vikash Sinha , Yanli Wang
CPC classification number: C07K16/244 , A61K45/06 , A61P17/06 , A61K9/0019 , A61K2039/505
Abstract: A method of treating mild to moderate psoriasis in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial dose and subsequent doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.
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公开(公告)号:US20240101662A1
公开(公告)日:2024-03-28
申请号:US18513931
申请日:2023-11-20
Applicant: Janssen Biotech, Inc.
Inventor: Ming-Chun Hsu , Shu Li , Bruce Randazzo , Kun Song , Yaowei Zhu
CPC classification number: C07K16/244 , A61P17/06 , A61K2039/505
Abstract: Anti-IL-12/IL-23p40 antibodies, such as ustekinumab, are used in methods and compositions for safe and effective treatment of psoriasis, particularly moderate to severe chronic plaque psoriasis, in pediatric patients. The methods and compositions address a clear unmet medical need in this patient population.
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公开(公告)号:US20200331996A1
公开(公告)日:2020-10-22
申请号:US16819629
申请日:2020-03-16
Applicant: Janssen Biotech, Inc.
Inventor: Ming-Chun Hsu , Shu Li , Bruce Randazzo , Kun Song , Yaowei Zhu
Abstract: Anti-IL-12/IL-23p40 antibodies, such as ustekinumab, are used in methods and compositions for safe and effective treatment of psoriasis, particularly moderate to severe chronic plaque psoriasis, in pediatric patients. The methods and compositions address a clear unmet medical need in this patient population.
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公开(公告)号:US20220289835A1
公开(公告)日:2022-09-15
申请号:US17734482
申请日:2022-05-02
Applicant: Janssen Biotech, Inc.
Inventor: Julianty Angsana , Patrick Branigan , Samuel DePrimo , Susan Flavin , Shu Li , Xeujun Liu , Ernesto Munoz , Bruce Randazzo
IPC: C07K16/24 , A61P17/06 , A61K39/395
Abstract: A method of treating psoriasis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves PASI90, PASI100 or IGA 0 or 1 score as measured 16, 24, 32, 40 and 48 weeks after initial treatment and the patient achieves higher efficacy than a patient treated with the secukinumab antibody.
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公开(公告)号:US20200157209A1
公开(公告)日:2020-05-21
申请号:US16688178
申请日:2019-11-19
Applicant: Janssen Biotech, Inc.
Inventor: Julianty Angsana , Patrick Branigan , Samuel DePrimo , Susan Flavin , Shu Li , Xuejun Liu , Ernesto Munoz , Bruce Randazzo
Abstract: A method of treating psoriasis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves PASI90, PASI100 or IGA 0 or 1 score as measured 16, 24, 32, 40 and 48 weeks after initial treatment and the patient achieves higher efficacy than a patient treated with the secukinumab antibody
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公开(公告)号:US20230014839A1
公开(公告)日:2023-01-19
申请号:US17931633
申请日:2022-09-13
Applicant: Janssen Biotech, Inc.
Inventor: Ming-Chun Hsu , Shu Li , Bruce Randazzo , Kun Song , Yaowei Zhu
Abstract: Anti-IL-12/IL-23p40 antibodies, such as ustekinumab, are used in methods and compositions for safe and effective treatment of psoriasis, particularly moderate to severe chronic plaque psoriasis, in pediatric patients. The methods and compositions address a clear unmet medical need in this patient population.
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公开(公告)号:US20220073603A1
公开(公告)日:2022-03-10
申请号:US17389533
申请日:2021-07-30
Applicant: Janssen Biotech, Inc.
Inventor: Ming-Chun Hsu , Shu Li , Bruce Randazzo , Kun Song , Yaowei Zhu
Abstract: Anti-IL-12/IL-23p40 antibodies, such as ustekinumab, are used in methods and compositions for safe and effective treatment of psoriasis, particularly moderate to severe chronic plaque psoriasis, in pediatric patients. The methods and compositions address a clear unmet medical need in this patient population.
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