-
公开(公告)号：US11919881B2
公开(公告)日：2024-03-05
申请号：US17696922
申请日：2022-03-17
发明人： Guozhang Xu , Tho V. Thieu , Zhijie Liu , Micheal D. Gaul
IPC分类号： C07D401/14
CPC分类号： C07D401/14
摘要： The present invention provides imidazole substituted pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
-
公开(公告)号：US20230091768A1
公开(公告)日：2023-03-23
申请号：US17696926
申请日：2022-03-17
发明人： Guozhang Xu , Boying Guo , Zhijie Liu , Jing Zhang , Micheal D. Gaul , Eugene B. Grant , Mark J. Macielag , Tianbao Lu , Tho V. Thieu
IPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention is directed to pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
-
公开(公告)号：US20230097157A1
公开(公告)日：2023-03-30
申请号：US17870156
申请日：2022-07-21
发明人： Guozhang Xu , Mark J. Macielag , Micheal D. Gaul , Tho V. Thieu , Zhijie Liu
IPC分类号： C07D471/04
摘要： The present invention is directed to bicyclic pyridinon-2-one and pyrimidin-4-one derivatives, stereoisomers, isotopologues, and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
-
公开(公告)号：US20220315561A1
公开(公告)日：2022-10-06
申请号：US17696922
申请日：2022-03-17
发明人： Guozhang Xu , Tho V. Thieu , Zhijie Liu , Micheal D. Gaul
IPC分类号： C07D401/14
摘要： The present invention provides imidazole substituted pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
-
公开(公告)号：US20240228465A1
公开(公告)日：2024-07-11
申请号：US18428046
申请日：2024-01-31
发明人： Guozhang Xu , Tho V. Thieu , Zhijie Liu , Micheal D. Gaul
IPC分类号： C07D401/14
CPC分类号： C07D401/14
摘要： The present invention provides imidazole substituted pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
-
公开(公告)号：US11814364B2
公开(公告)日：2023-11-14
申请号：US17696926
申请日：2022-03-17
发明人： Guozhang Xu , Boying Guo , Zhijie Liu , Jing Zhang , Micheal D. Gaul , Eugene B. Grant , Mark J. Macielag , Tianbao Lu , Tho V. Thieu
IPC分类号： C07D401/14 , C07D417/14 , C07D413/14 , C07D405/14
CPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention is directed to pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.012 秒)
