公开(公告)号：US20030059419A1

公开(公告)日：2003-03-27

申请号：US10298402

申请日：2002-11-18

Applicant: Japan Science and Technology Corporation

Inventor： Shizuo Akira ,  Takahiro Shimada

IPC: A61K038/45 ,  C07H021/04 ,  C12N009/12 ,  C12P021/02 ,  C12N005/06

CPC classification number: C12N9/1205 ,  A61K38/00

Abstract: Novel IkB kinase IKK-i which is a novel serine/threonine kinase capable of activating a transcription factor NF-kB which inhibits the expression of various genes relating to immune response; a gene encoding the same; and medicinal compositions containg the same.

Abstract translation: 新型IkB激酶IKK-i，其是能够激活转录因子NF-kB的新型丝氨酸/苏氨酸激酶，其抑制与免疫应答相关的各种基因的表达; 编码该基因的基因; 和含有其的药物组合物。