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公开(公告)号:US08378068B2
公开(公告)日:2013-02-19
申请号:US12705094
申请日:2010-02-12
IPC分类号: C07K14/00
CPC分类号: A61K38/1709 , A61K38/16 , C07K14/775
摘要: Provided are peptides, compositions thereof, and methods for treating or preventing dyslipidemia, a cardiovascular disease, endothelial dysfunction, a macrovascular disorder, or a microvascular disorder.
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公开(公告)号:US06953840B2
公开(公告)日:2005-10-11
申请号:US10629892
申请日:2003-07-29
CPC分类号: A61K38/1709 , A61K47/543 , A61K47/6905 , A61K2300/00
摘要: The invention provides methods and compositions for treating disorders using non-human animal Apolipoprotein A-I (ApoA-I) protein. The invention provides methods and compositions for treating disorders in animals, including humans, associated with dyslipidemia, including hyperlipidemia, hyperlipoproteinemia, hypertriglyceridemia, hypercholesterolemia, HDL deficiency, ApoA-I deficiency, cardiovascular disease, atherosclerosis, restenosis, and other disorders such as septic shock and viral infections.
摘要翻译: 本发明提供了使用非人动物载脂蛋白A-I(ApoA-I)蛋白治疗病症的方法和组合物。 本发明提供了用于治疗与血脂异常相关的动物(包括人)的疾病的方法和组合物,包括高脂血症,高脂蛋白血症,高甘油三酯血症,高胆固醇血症,HDL缺乏症,ApoA-I缺乏症,心血管疾病,动脉粥样硬化,再狭窄和其它疾病如败血性休克 和病毒感染。
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公开(公告)号:US20060014692A1
公开(公告)日:2006-01-19
申请号:US11223838
申请日:2005-09-08
申请人: Lingyu Zhu , Narendra Lalwani , Jean-Louis Dasseux
发明人: Lingyu Zhu , Narendra Lalwani , Jean-Louis Dasseux
IPC分类号: A61K38/17
CPC分类号: A61K38/1709 , A61K47/543 , A61K47/6905 , A61K2300/00
摘要: The invention provides methods and compositions for treating disorders using non-human animal Apolipoprotein A-I (ApoA-I) protein. The invention provides methods and compositions for treating disorders in animals, including humans, associated with dyslipidemia, including hyperlipidemia, hyperlipoproteinemia, hypertriglyceridemia, hypercholesterolemia, HDL deficiency, ApoA-I deficiency, cardiovascular disease, atherosclerosis, restenosis, and other disorders such as septic shock and viral infections.
摘要翻译: 本发明提供了使用非人动物载脂蛋白A-I(ApoA-I)蛋白治疗病症的方法和组合物。 本发明提供了用于治疗与血脂异常相关的动物(包括人)的疾病的方法和组合物,包括高脂血症,高脂蛋白血症,高甘油三酯血症,高胆固醇血症,HDL缺乏症,ApoA-I缺乏症,心血管疾病,动脉粥样硬化,再狭窄和其它疾病如败血性休克 和病毒感染。
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公开(公告)号:US20100015220A1
公开(公告)日:2010-01-21
申请号:US12469653
申请日:2009-05-20
申请人: John R. WETTERAU , Lingyu Zhu , Robert A. Scott , Constance H. Keyserling , Jean-Louis H. Dasseux , Daniela Carmen Oniciu , Pierre Autant , Roger Kravtzoff , Catherine Castan , Hervé Guillard
发明人: John R. WETTERAU , Lingyu Zhu , Robert A. Scott , Constance H. Keyserling , Jean-Louis H. Dasseux , Daniela Carmen Oniciu , Pierre Autant , Roger Kravtzoff , Catherine Castan , Hervé Guillard
CPC分类号: A61K31/455 , A61K31/616 , A61K2300/00
摘要: Provided are pharmaceutical compositions and methods for preventing or reducing niacin-induced flushing comprising an aspirin component and a niacin component having different release profiles. Also provided are methods and compositions for preventing or reducing niacin-induced flushing comprising niacin, aspirin and a lipid-lowering drug other than niacin.
摘要翻译: 提供了用于预防或减少烟酸诱发的潮红的药物组合物和方法,其包含具有不同释放特征的阿司匹林组分和烟酸组分。 还提供了用于预防或减少烟酸诱发的潮红的方法和组合物,其包含烟酸,阿司匹林和除了烟酸以外的降脂药物。
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