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公开(公告)号：US07354605B2
公开(公告)日：2008-04-08
申请号：US11336699
申请日：2006-01-20
摘要： According to the present invention there are provided antimicrobial catheters and other medical devices having controlled release of an antimicrobial metal or metal ion. Specifically, antimicrobial catheters and other medical devices manifest antimicrobial properties as a result of the incorporation therein of antimicrobial microcapsules comprising an inorganic antimicrobial agent and a hydrophilic polymer.
摘要翻译： 根据本发明，提供了具有抗微生物金属或金属离子的受控释放的抗微生物导管和其它医疗装置。 具体地，抗微生物导管和其它医疗装置由于其中包含无机抗微生物剂和亲水性聚合物的抗微生物微胶囊的结合而表现出抗菌性能。
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公开(公告)号：US07357949B2
公开(公告)日：2008-04-15
申请号：US10032372
申请日：2001-12-21
摘要： The invention relates to a microcapsule comprising an inorganic antimicrobial agent coated with a hydrophilic polymer. The hydrophilic polymer is able to absorb sufficient water as to enable the action of the encapsulated antimicrobial agent. These microcapsules are useful to impart antimicrobial activity and can be used in polymer compositions, sprays and coatings. A method of preparing the microcapsule by treatment of the antimicrobial agent with a solution of the hydrophilic polymer is provided. Another embodiment of the invention is a method of preparing the microcapsule by coating of the antimicrobial agent with a polymer precursor followed by treatment with a reactive ingredient. Another embodiment of the invention is a method of preparing the microcapsule by melt compounding the antimicrobial agent with the hydrophilic polymer followed by grinding to the desired particle size. Polymer compositions comprising the microcapsules and a matrix polymer are also provided. Another embodiment of the invention is an article prepared from the polymer compositions comprising the microcapsules and a matrix polymer.
摘要翻译： 本发明涉及包含用亲水性聚合物涂覆的无机抗微生物剂的微胶囊。 亲水性聚合物能够吸收足够的水以使得能够包封的抗微生物剂的作用。 这些微胶囊可用于赋予抗微生物活性，并可用于聚合物组合物，喷雾剂和涂料。 提供了通过用亲水性聚合物溶液处理抗微生物剂来制备微胶囊的方法。 本发明的另一个实施方案是通过用聚合物前体涂覆抗微生物剂然后用活性成分处理来制备微胶囊的方法。 本发明的另一个实施方案是通过将抗微生物剂与亲水性聚合物熔融混合，然后研磨成所需的粒度来制备微胶囊的方法。 还提供了包含微胶囊和基质聚合物的聚合物组合物。 本发明的另一个实施方案是由包含微胶囊和基质聚合物的聚合物组合物制备的制品。
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3.发明授权
公开(公告)号：US5962541A
公开(公告)日：1999-10-05
申请号：US95081
申请日：1998-06-10
CPC分类号： C08G18/10 , C08J9/144 , C08G2101/0025 , C08G2101/005 , C08J2375/04
摘要： NCO-terminated prepolymers are made by reacting a polymeric diphenylmethane diisocyanate (PMDI) and a polyol having a functionality of from about 1.8 to about 4.0 and a molecular weight of from about 400 to about 2,000. The PMDI and polyol are reacted in amounts such that the equivalent ratio of isocyanate groups to hydroxyl groups is from about 15:1 to about 160:1. These prepolymers are useful in the production of polyurethane foams, particularly laminated foams.
摘要翻译： NCO封端的预聚物通过聚合二苯基甲烷二异氰酸酯（PMDI）和官能度为约1.8至约4.0，分子量为约400至约2,000的多元醇反应制备。 PMDI和多元醇的反应量使得异氰酸酯基与羟基的当量比为约15:1至约160:1。 这些预聚物可用于生产聚氨酯泡沫，特别是层压泡沫。
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