公开(公告)号：US20180305344A1

公开(公告)日：2018-10-25

申请号：US15779353

申请日：2016-11-23

申请人： Jeffrey William STROVEL ,  Makoto YOSHIOKA ,  David J. MALONEY ,  Shyh Ming YANG ,  Ajit JADHAV ,  Daniel Jason URBAN ,  ConverGene LLC

发明人： Jeffrey William Strovel ,  Makoto Yoshioka ,  David J. Maloney ,  Shyh Ming Yang ,  Ajit Jadhav ,  Daniel Jason Urban

IPC分类号： C07D413/04 ,  C07D413/14 ,  C07D239/95 ,  C07D403/04 ,  C07D401/04 ,  C07D401/14 ,  C07D417/14 ,  C07D471/04 ,  C07D471/10 ,  A61P39/00

CPC分类号： C07D413/04 ,  A61P39/00 ,  C07D239/84 ,  C07D239/95 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D471/10

摘要： The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.

公开(公告)号：US10508106B2

公开(公告)日：2019-12-17

申请号：US15779353

申请日：2016-11-23

申请人： ConverGene LLC ,  The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： Jeffrey William Strovel ,  Makoto Yoshioka ,  David J. Maloney ,  Shyh Ming Yang ,  Ajit Jadhav ,  Daniel Jason Urban

IPC分类号： C07D413/04 ,  C07D413/14 ,  C07D401/04 ,  C07D239/84 ,  C07D471/04 ,  C07D471/10 ,  A61P39/00 ,  C07D239/95 ,  C07D401/14 ,  C07D403/04 ,  C07D417/14

摘要： The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.

公开(公告)号：US20200223836A1

公开(公告)日：2020-07-16

申请号：US16685128

申请日：2019-11-15

申请人： ConverGene LLC ,  The United States of America, as represented by the Secretary,Department of Health and Human Service

发明人： Jeffrey William Strovel ,  Makoto Yoshioka ,  David J. Maloney ,  Shyh Ming Yang ,  Ajit Jadhav ,  Daniel Jason Urban, JR.

IPC分类号： C07D413/04 ,  C07D413/14 ,  C07D401/04 ,  C07D471/04 ,  C07D471/10 ,  C07D239/84 ,  A61P39/00 ,  C07D239/95 ,  C07D401/14 ,  C07D403/04 ,  C07D417/14

摘要： The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.