ALLERGEN MUTANTS
    1.
    发明申请
    ALLERGEN MUTANTS 审中-公开
    过敏原

    公开(公告)号:US20110052639A1

    公开(公告)日:2011-03-03

    申请号:US12837242

    申请日:2010-07-15

    IPC分类号: A61K39/35 A61P37/08

    摘要: Novel recombinant allergens with multiple mutations and reduced IgE binding affinity are disclosed. The allergens are mutants of naturally occurring allergens. The overall α-carbon backbone tertiary structure is essentially preserved. Also disclosed is a method for preparing such recombinant allergens as well as uses thereof.

    摘要翻译: 公开了具有多重突变和降低的IgE结合亲和力的新型重组变应原。 过敏原是天然存在的变应原的突变体。 总体上,α-碳骨架三级结构基本保持不变。 还公开了制备这种重组变应原及其应用的方法。