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公开(公告)号:US07615353B1
公开(公告)日:2009-11-10
申请号:US12498183
申请日:2009-07-06
申请人: Jie Lin , Murray Robinson , Bin Feng , Wenping Kathryn Sun
发明人: Jie Lin , Murray Robinson , Bin Feng , Wenping Kathryn Sun
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要: A diagnostic method for predicting quantitatively whether a human tumor will be responsive or resistant (non-responsive) to treatment with the VEGF inhibitor, tivozanib (AV-951), is disclosed. The test is based on application of an algorithm to measurements of expression levels of the genes in a predictive gene set.
摘要翻译: 公开了一种诊断方法,用于定量地预测人肿瘤是否对VEGF抑制剂替利扎布(AV-951)的治疗具有响应性或抗性(非响应性)。 该测试基于将算法应用于预测基因组中基因表达水平的测量。