公开(公告)号：US07601952B2

公开(公告)日：2009-10-13

申请号：US11778954

申请日：2007-07-17

申请人： Jim Hager ,  Bruce Thomson

发明人： Jim Hager ,  Bruce Thomson

IPC分类号： H01J49/00

CPC分类号： H01J49/4225 ,  H01J49/004 ,  H01J49/4265 ,  H01J49/4285

摘要： A method of operating a mass spectrometer having a rod set is provided. The rod set has a first end, a second end opposite to the first end, and a longitudinal axis extending between the first end and the second end. The method comprises a) admitting ions into the rod set; b) trapping at least some of the ions in the rod set by i) producing a first barrier field at a first end member adjacent to the first end of the rod set, ii) producing a second barrier field at a second end member adjacent to the second end of the rod set, and iii) providing an aggregate field comprising an RF field between the rods of the rod set; c) selecting a first selected mass to charge ratio of a first group of ions in the ions; d) determining a first excitement level of a selected characteristic of the aggregate field for the first group of ions; e) adjusting the selected characteristic of the aggregate field to the first excitement level to resonantly excite the first group of ions to mass selectively eject the first group of ions from the rod set past the barrier field; and, f) maintaining the selected characteristic of the aggregate field at the first excitement level during an excitement time interval wherein the excitation time interval is at least 1 millisecond.

摘要翻译： 提供了具有棒组的操作质谱仪的方法。 杆组具有第一端，与第一端相对的第二端和在第一端和第二端之间延伸的纵向轴线。 该方法包括：a）将离子进入棒组; b）通过以下步骤捕获所述棒组中的至少一些离子：i）在与所述棒组的第一端相邻的第一端构件处产生第一屏障场，ii）在邻近所述杆组的第二端构件处产生第二屏障场 所述杆组的第二端，以及iii）提供包括所述杆组的杆之间的RF场的聚集场; c）选择离子中的第一组离子的第一选择质量与电荷比; d）确定第一组离子的聚集场的选定特征的第一兴奋度; e）将聚集场的所选特征调整到第一兴奋水平以共振地激发第一组离子以质量选择性地从穿过屏障场的棒组中弹出第一组离子; 以及f）在所述激发时间间隔至少为1毫秒的兴奋时间间隔期间将所述聚集场的选定特性保持在所述第一兴奋度水平。

公开(公告)号：US20080017789A1

公开(公告)日：2008-01-24

申请号：US11778954

申请日：2007-07-17

申请人： Jim Hager ,  Bruce Thomson

发明人： Jim Hager ,  Bruce Thomson

IPC分类号： H01J49/00

CPC分类号： H01J49/4225 ,  H01J49/004 ,  H01J49/4265 ,  H01J49/4285

摘要： A method of operating a mass spectrometer having a rod set is provided. The rod set has a first end, a second end opposite to the first end, and a longitudinal axis extending between the first end and the second end. The method comprises a) admitting ions into the rod set; b) trapping at least some of the ions in the rod set by i) producing a first barrier field at a first end member adjacent to the first end of the rod set, ii) producing a second barrier field at a second end member adjacent to the second end of the rod set, and iii) providing an aggregate field comprising an RF field between the rods of the rod set; c) selecting a first selected mass to charge ratio of a first group of ions in the ions; d) determining a first excitement level of a selected characteristic of the aggregate field for the first group of ions; e) adjusting the selected characteristic of the aggregate field to the first excitement level to resonantly excite the first group of ions to mass selectively eject the first group of ions from the rod set past the barrier field; and, f) maintaining the selected characteristic of the aggregate field at the first excitement level during an excitement time interval wherein the excitation time interval is at least 1 millisecond.

摘要翻译： 提供了具有棒组的操作质谱仪的方法。 杆组具有第一端，与第一端相对的第二端和在第一端和第二端之间延伸的纵向轴线。 该方法包括：a）将离子进入棒组; b）通过以下步骤捕获所述棒组中的至少一些离子：i）在与所述棒组的第一端相邻的第一端构件处产生第一屏障场，ii）在邻近所述杆组的第二端构件处产生第二屏障场 所述杆组的第二端，以及iii）提供包括所述杆组的杆之间的RF场的聚集场; c）选择离子中的第一组离子的第一选择质量与电荷比; d）确定第一组离子的聚集场的选定特征的第一兴奋度; e）将聚集场的所选特征调整到第一兴奋水平以共振地激发第一组离子以质量选择性地从穿过屏障场的棒组中弹出第一组离子; 以及f）在所述激发时间间隔至少为1毫秒的兴奋时间间隔期间将所述聚集场的选定特性保持在所述第一兴奋度水平。