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公开(公告)号:US20090092602A1
公开(公告)日:2009-04-09
申请号:US12184205
申请日:2008-07-31
IPC分类号: A61K39/395 , A61P7/02
CPC分类号: C07K16/36 , A61K2039/505 , C07K16/467 , C07K2317/24 , C07K2319/00
摘要: Disclosed is a method for preventing or treating thrombosis in a mammal such as a primate and particularly a human patient. A preferred method includes administering to the mammal a therapeutically effective amount of at least one humanized antibody, chimeric antibody, or fragment thereof that binds specifically to human tissue factor (TF). Additional methods and kits are provided.
摘要翻译: 公开了一种预防或治疗哺乳动物如灵长类动物,特别是人类患者血栓形成的方法。 优选的方法包括向哺乳动物施用治疗有效量的与人组织因子(TF)特异性结合的至少一种人源化抗体,嵌合抗体或其片段。 提供其他方法和试剂盒。