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公开(公告)号:US5037883A
公开(公告)日:1991-08-06
申请号:US438352
申请日:1989-11-17
申请人: Jindrich Kopecek , Pavla Rejmanova , Jiri Strohalm , Karel Ulbrich , Blanka Rihova , Vladimir Chytry , John B. Lloyd , Ruth Duncan
发明人: Jindrich Kopecek , Pavla Rejmanova , Jiri Strohalm , Karel Ulbrich , Blanka Rihova , Vladimir Chytry , John B. Lloyd , Ruth Duncan
IPC分类号: A61K38/00 , A61K20060101 , A61K31/00 , A61K31/70 , A61K45/00 , A61K47/00 , A61K47/48 , A61P35/00
CPC分类号: A61K47/48692 , A61K47/48176 , Y10S530/811 , Y10S530/812 , Y10S530/815 , Y10S530/816
摘要: A polymeric drug comprising an inert synthetic polymeric carrier combined through aminoacid or peptide spacers with a bioactive molecule, a targeting moiety, and an optional cross-linkage, comprises:(a) 5.0 to 99.7 mol % of units derived from N-(2-hydroxypropyl)methacrylamide,(b) 0.2 to 20.0 mol % of units derived from an N-methylacrylcylated peptide, the peptide groups being bound to a bioactive moiety,(c) 0.1 to 94.8 mol % of units derived from N-methacrylamide, N-methacrylic acid or an N-methacrylolated aminoacid or peptide, to which are bound a determinant capable of interacting with specific receptors on cell surfaces,(d) optionally, 0 to 5 mol % of units derived from an N-methacryloylated peptide, the peptide groups being bound to a linking group which is similarly to a similar peptide group attached to another polymer chain, and(e) optionally, as a bioassay label, 0 to 2 mol % units derived from N-methyacryloylated tyrosinamide.
摘要翻译: 包含通过氨基酸或肽间隔物与生物活性分子,靶向部分和任选的交联结合的惰性合成聚合物载体的聚合物药物包括:(a)5.0-99.7mol%衍生自N-(2- 羟丙基)甲基丙烯酰胺,(b)衍生自N-甲基丙烯酰化肽的单元的0.2〜20.0摩尔%,所述肽基团与生物活性部分结合,(c)0.1〜94.8摩尔%的来源于N-甲基丙烯酰胺,N- 甲基丙烯酸或N-甲基丙烯酰化的氨基酸或肽,其结合能够与细胞表面上的特异性受体相互作用的决定簇,(d)任选地0至5摩尔%的衍生自N-甲基丙烯酰基化肽的单元,所述肽基团 与类似于连接于另一聚合物链的肽基团的连接基团结合,和(e)任选地,作为生物测定标记物,衍生自N-甲基丙烯酰基化酪氨酰胺的0至2摩尔%的单位。
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公开(公告)号:US3977545A
公开(公告)日:1976-08-31
申请号:US545118
申请日:1975-01-29
申请人: John B. Lloyd
发明人: John B. Lloyd
CPC分类号: B60P1/431
摘要: A loading apparatus for pickup trucks and the like is characterized by elongated interchangeable ramp sections releasably secured to the rear end of a special platform on the bed of the pickup truck so that the ramp sections are releasably attachable for downward extension from the platform to the ground, and further are slidable into a storage position beneath the platform when not in use. Alternate types of platforms have been devised to vary the effective width of the pickup truck bed to accommodate one or more vehicles, and the ramp sections include different types of tread surfaces which are interchangeable to facilitate loading and unloading of different types of vehicles.
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公开(公告)号:US4091946A
公开(公告)日:1978-05-30
申请号:US664770
申请日:1976-03-08
申请人: Robert W. Kraeft , John B. Lloyd
发明人: Robert W. Kraeft , John B. Lloyd
CPC分类号: B60P3/035 , B60P1/48 , Y10S414/124
摘要: Cable reels are loaded, unloaded, transferred or otherwise handled relative to the flatbed of a vehicle by a pivotally mounted lift assembly which includes a main rotary shaft having two or more extended lift arms rigidly attached in a generally U-shaped configuration. The main rotary shaft, when attached along one edge of the flat bed, is capable of pivoting through 180.degree. rotation by hydraulic rams or the like, and the lift arms include an arrangement for securing the cargo outwardly of the shaft with hydraulically actuated gripper finger arrangements. Arrangement of a plurality of lift assemblies in tandem so that the extremities of the lift arms are on intersecting arcs enables the cargo to be lifted from the ground surface onto the flatbed and transferred to different selected positions. Power winches appropriately positioned or peripheral engagement of cable reel containers allow rotary cargo for cable reel winding or unwinding.
摘要翻译: 电缆卷盘通过枢转安装的提升组件相对于车辆的平板装载,卸载,转移或以其他方式处理,该提升组件包括主旋转轴,该主旋转轴具有刚性地以大致U形构型刚性地连接的两个或更多个延长的提升臂。 主旋转轴沿着平板床的一个边缘安装时,能够通过液压柱塞等旋转180°,并且提升臂包括用液压驱动的夹爪手指将货物固定在轴外的装置 安排 多个提升组件串联布置,使得提升臂的末端在交叉弧上,使得货物能够从地面被提升到平板上并被转移到不同的选定位置。 电动绞盘适当定位或电缆卷盘容器的周边接合允许旋转货物用于电缆卷筒卷绕或展开。
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