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1.发明申请Aza-bicyclic n-biarylamides with affinity for the alpha-7 nicotinic acetylcholine receptor 有权对α-7烟碱乙酰胆碱受体具有亲和力的氮杂双环正二芳基酰胺公开(公告)号：US20050154045A1
公开(公告)日：2005-07-14
申请号：US10508108
申请日：2003-03-03
申请人： Joachim Luithle , Frank-Gerhard Boss , Christiana Erb , Katrin Schnizler , Timo Flessner , Marja Kampen , Christoph Methfessel , Frank-Thorsten Hafner
发明人： Joachim Luithle , Frank-Gerhard Boss , Christiana Erb , Katrin Schnizler , Timo Flessner , Marja Kampen , Christoph Methfessel , Frank-Thorsten Hafner
IPC分类号： C07D453/04 , A61K31/439 , A61K31/5377 , A61P9/10 , A61P25/00 , A61P25/04 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P31/18 , A61P43/00 , C07D453/02 , A61K31/407 , C07D487/02
CPC分类号： C07D453/02
摘要： The invention relates to novel 1-aza-bicyclic N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
摘要翻译： 本发明涉及新的1-氮杂 - 双环N-二芳基酰胺，其生产和使用方法，用于生产用于治疗和/或预防疾病以及改善感知，浓度，学习能力和记忆力的药物。
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公开(公告)号：US20060160877A1
公开(公告)日：2006-07-20
申请号：US10516777
申请日：2003-06-02
申请人： Joachim Luithle , Frank-Gerhard Boss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja Kampen , Franz-Josef Staay
发明人： Joachim Luithle , Frank-Gerhard Boss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja Kampen , Franz-Josef Staay
IPC分类号： C07D487/04 , A01N43/38
CPC分类号： C07D453/02
摘要： The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新的2-杂芳基羧酰胺及其用于制备用于治疗和/或预防疾病和改善感知，浓度，学习和/或记忆的药物的用途。
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3.发明授权Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists 有权氮杂双环氨基甲酸酯及其作为α-7烟碱乙酰胆碱受体激动剂的用途公开(公告)号：US08153799B2
公开(公告)日：2012-04-10
申请号：US12871495
申请日：2010-08-30
申请人： Timo Flessner , Frank-Gerhard Boss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef Van Der Staay
发明人： Timo Flessner , Frank-Gerhard Boss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef Van Der Staay
IPC分类号： C07D453/02 , C07D307/00
CPC分类号： C07D453/02
摘要： The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory.
摘要翻译： 本发明涉及新的苯并噻吩 - ，苯并呋喃和吲哚脲，以及其用于制备用于治疗和/或预防疾病和改善感知，集中，学习和/或记忆的药物的用途。
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4.发明授权Aza-bicyclic N-biarylamides with affinity for the α7 nicotinic acetylcholine receptor 有权对α7烟碱乙酰胆碱受体具有亲和力的氮杂 - 双环N-二芳基酰胺公开(公告)号：US07138410B2
公开(公告)日：2006-11-21
申请号：US10508108
申请日：2003-03-03
申请人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Katrin Schnizler , Timo Flessner , Marja van Kampen , Christoph Methfessel , Frank-Thorsten Hafner
发明人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Katrin Schnizler , Timo Flessner , Marja van Kampen , Christoph Methfessel , Frank-Thorsten Hafner
IPC分类号： A61K31/439 , A61K31/5377 , C07D453/02 , C07D413/12
CPC分类号： C07D453/02
摘要： The invention relates to novel 1-aza-bicyclic N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
摘要翻译： 本发明涉及新的1-氮杂 - 双环N-二芳基酰胺，其生产和使用方法，用于生产用于治疗和/或预防疾病以及改善感知，浓度，学习能力和记忆力的药物。
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公开(公告)号：US20070037844A1
公开(公告)日：2007-02-15
申请号：US10508106
申请日：2003-03-03
申请人： Joachim Luithle , Frank-Gerhard Bob , Christina Erb , Katrin Schnizler , Timo Flessner , Marja Kampen , Christoph Methfessel
发明人： Joachim Luithle , Frank-Gerhard Bob , Christina Erb , Katrin Schnizler , Timo Flessner , Marja Kampen , Christoph Methfessel
IPC分类号： A61K31/46
CPC分类号： C07D453/02 , A61K31/439 , C07D453/04
摘要： The invention relates to novel amides of acetic and propionic acids, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
摘要翻译： 本发明涉及乙酸和丙酸的新型酰胺，其生产和使用方法，用于生产用于治疗和/或预防疾病以及改善感知，浓度，学习能力和记忆力的药物。
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公开(公告)号：US20120258964A1
公开(公告)日：2012-10-11
申请号：US13412946
申请日：2012-03-06
申请人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja Van Kampen , Franz-Josef Van Der Staay
发明人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja Van Kampen , Franz-Josef Van Der Staay
IPC分类号： C07D453/02 , A61K31/5377 , A61P25/28 , A61K31/506 , A61P25/00 , A61K31/439 , A61K31/496
CPC分类号： C07D453/02
摘要： The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新的2-杂芳基羧酰胺及其用于制备用于治疗和/或预防疾病和改善感知，浓度，学习和/或记忆的药物的用途。
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公开(公告)号：US20110263591A1
公开(公告)日：2011-10-27
申请号：US13179957
申请日：2011-07-11
申请人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja van Kampen , Franz-Josef van der Staay
发明人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja van Kampen , Franz-Josef van der Staay
IPC分类号： A61K31/439 , A61K31/506 , A61P25/28 , A61K31/5377
CPC分类号： C07D453/02
摘要： The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新的2-杂芳基羧酰胺及其用于制备用于治疗和/或预防疾病和改善感知，浓度，学习和/或记忆的药物的用途。
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8.发明申请AZABICYCLIC CARBAMATES AND THEIR USE AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS 有权异丁烯酸碳酸酯及其作为ALPHA-7 NICOTINIC乙酰胆碱受体激动剂公开(公告)号：US20100324085A1
公开(公告)日：2010-12-23
申请号：US12871495
申请日：2010-08-30
申请人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Maria-Van Kampen , Franz-Josef Van der Staay
发明人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Maria-Van Kampen , Franz-Josef Van der Staay
IPC分类号： A61K31/4375 , C07D453/02 , A61P25/00
CPC分类号： C07D453/02
摘要： The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory.
摘要翻译： 本发明涉及新的苯并噻吩 - ，苯并呋喃和吲哚脲，以及其用于制备用于治疗和/或预防疾病和改善感知，集中，学习和/或记忆的药物的用途。
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9.发明申请公开(公告)号：US20130060039A1
公开(公告)日：2013-03-07
申请号：US13441407
申请日：2012-04-06
申请人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef van der Staay
发明人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef van der Staay
IPC分类号： C07D453/02
CPC分类号： C07D453/02
摘要： The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory.
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10.发明申请Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists 有权氮杂双环氨基甲酸酯及其作为α-7烟碱乙酰胆碱受体激动剂的用途公开(公告)号：US20060106096A1
公开(公告)日：2006-05-18
申请号：US10522611
申请日：2003-07-14
申请人： Timo Flessner , Frank-Gerhard Bossw , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef Van der Staay
发明人： Timo Flessner , Frank-Gerhard Bossw , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef Van der Staay
IPC分类号： C07D307/87 , A61K31/343
CPC分类号： C07D453/02
摘要： The invention relates to novel benzothiophene-, benzofuran- and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新的苯并噻吩 - ，苯并呋喃 - 和吲哚脲，以及其用于制备用于治疗和/或预防疾病以及改善感知，浓度，学习和/或记忆的药物的用途。
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