公开(公告)号：US09623002B2

公开(公告)日：2017-04-18

申请号：US14827343

申请日：2015-08-17

申请人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M. A. Akbarsha

发明人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M. A. Akbarsha

IPC分类号： A61K9/66 ,  A61K38/00 ,  A61K31/34 ,  C07D307/00 ,  A61K31/343 ,  A61K9/00 ,  A61K47/10 ,  A61K47/26 ,  A61K9/107 ,  A61K47/44

CPC分类号： A61K31/343 ,  A61K9/0014 ,  A61K9/1075 ,  A61K47/10 ,  A61K47/26 ,  A61K47/44

摘要： A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The pharmaceutical composition may comprise Anisomelic acid or salt thereof in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a co-solvents or surfactant or a combination thereof. A method of treating or preventing of cancer in a mammal, wherein the p53 pathway is deregulated by viral oncoproteins, is also provided.

公开(公告)号：US09345687B2

公开(公告)日：2016-05-24

申请号：US14423711

申请日：2013-08-28

申请人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M. A. Akbarsha

发明人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M. A. Akbarsha

IPC分类号： A61K9/66 ,  A61K38/00 ,  A61K31/34 ,  C07D307/00 ,  A61K31/365 ,  A61K9/00 ,  A61K9/107 ,  A61K9/48

CPC分类号： A61K31/365 ,  A61K9/0014 ,  A61K9/107 ,  A61K9/4825

摘要： A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The pharmaceutical composition may comprise Anisomelic acid or salt thereof in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a co-solvents or surfactant or a combination thereof. A method of treating or preventing of cancer in a mammal, wherein the p53 pathway is deregulated by viral oncoproteins, is also provided.

摘要翻译： 一种用于哺乳动物抗病毒治疗的药物组合物，其包含治疗有效量的茴香酸或其盐。 药物组合物可包含水包油乳液中的非离子酸或其盐，例如至少一种油和至少一种表面活性剂的各向同性混合物，或者在亲水性溶剂和共溶剂或表面活性剂 或其组合。 还提供了治疗或预防哺乳动物中癌症的方法，其中p53途径被病毒癌蛋白质解除调节。

公开(公告)号：US20160136126A1

公开(公告)日：2016-05-19

申请号：US14827343

申请日：2015-08-17

申请人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M.A. Akbarsha

发明人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M.A. Akbarsha

IPC分类号： A61K31/343 ,  A61K9/00

CPC分类号： A61K31/343 ,  A61K9/0014 ,  A61K9/1075 ,  A61K47/10 ,  A61K47/26 ,  A61K47/44

摘要： A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The pharmaceutical composition may comprise Anisomelic acid or salt thereof in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a co-solvents or surfactant or a combination thereof. A method of treating or preventing of cancer in a mammal, wherein the p53 pathway is deregulated by viral oncoproteins, is also provided.

公开(公告)号：US20150202180A1

公开(公告)日：2015-07-23

申请号：US14423711

申请日：2013-08-28

申请人： John ERIKSSON ,  Preethy Pau ,  Emilia PEUHU ,  M.A. AKBARSHA

发明人： John E. Eriksson ,  Preethy Paul ,  Emilia Peuhu ,  M.A. Akbarsha

IPC分类号： A61K31/365 ,  A61K9/48

CPC分类号： A61K31/365 ,  A61K9/0014 ,  A61K9/107 ,  A61K9/4825

摘要： A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The pharmaceutical composition may comprise Anisomelic acid or salt thereof in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a co-solvents or surfactant or a combination thereof. A method of treating or preventing of cancer in a mammal, wherein the p53 pathway is deregulated by viral oncoproteins, is also provided.

摘要翻译： 一种用于哺乳动物抗病毒治疗的药物组合物，其包含治疗有效量的茴香酸或其盐。 药物组合物可包含水包油乳液中的非离子酸或其盐，例如至少一种油和至少一种表面活性剂的各向同性混合物，或者在亲水性溶剂和共溶剂或表面活性剂 或其组合。 还提供了治疗或预防哺乳动物中癌症的方法，其中p53途径被病毒癌蛋白质解除调节。