公开(公告)号：US08022076B2

公开(公告)日：2011-09-20

申请号：US10864771

申请日：2004-06-10

申请人： John Ford ,  Nicholas John Palmer ,  John Frederick Atherall ,  David John Madge ,  Brad Sherborne ,  Mark Bushfield ,  Edward Benedict Stevens

发明人： John Ford ,  Nicholas John Palmer ,  John Frederick Atherall ,  David John Madge ,  Brad Sherborne ,  Mark Bushfield ,  Edward Benedict Stevens

IPC分类号： C07D495/04 ,  A61K31/519 ,  A61P9/06

CPC分类号： A61K31/495 ,  C07D495/04

摘要： This invention relates to novel compound of formula (I) or pharmaceutically acceptable salts thereof. The invention is also directed to the uses of compounds having formula (I) in the treatment or prevention of diseases or disorders which requires potassium channel inhibition to an animal, mammal or human in need thereof. The invention is also directed to the use of compounds having formula (I) in the treatment or prevention of arrhythmia to an animal, mammal or human in need thereof.

摘要翻译： 本发明涉及新的式（I）化合物或其药学上可接受的盐。 本发明还涉及具有式（I）的化合物在治疗或预防需要钾通道抑制的疾病或病症中对于有需要的动物，哺乳动物或人的用途。 本发明还涉及具有式（I）的化合物在治疗或预防心律失常的用途对于有需要的动物，哺乳动物或人类的用途。

公开(公告)号：US20050026935A1

公开(公告)日：2005-02-03

申请号：US10864771

申请日：2004-06-10

申请人： John Ford ,  Nicholas Palmer ,  John Atherall ,  David Madge ,  Brad Sherborne ,  Mark Bushfield ,  Edward Stevens

发明人： John Ford ,  Nicholas Palmer ,  John Atherall ,  David Madge ,  Brad Sherborne ,  Mark Bushfield ,  Edward Stevens

IPC分类号： A61K31/495 ,  A61P9/00 ,  C07D495/04 ,  A61K31/519 ,  C07D498/02

CPC分类号： A61K31/495 ,  C07D495/04

摘要： This invention relates to novel compound of formula (I) or pharmaceutically acceptable salts thereof. The invention is also directed to the uses of compounds having formula (I) in the treatment or prevention of diseases or disorders which requires potassium channel inhibition to an animal, mammal or human in need thereof. The invention is also directed to the use of compounds having formula (I) in the treatment or prevention of arrhythmia to an animal, mammal or human in need thereof.

摘要翻译： 本发明涉及新的式（I）化合物或其药学上可接受的盐。 本发明还涉及具有式（I）的化合物在治疗或预防需要钾通道抑制的疾病或病症中对于有需要的动物，哺乳动物或人的用途。 本发明还涉及具有式（I）的化合物在治疗或预防心律失常的用途对于有需要的动物，哺乳动物或人类的用途。