公开(公告)号：US20120107134A1

公开(公告)日：2012-05-03

申请号：US12915477

申请日：2010-10-29

申请人： John Wesley Harris, JR. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Xiaoyong Fu

发明人： John Wesley Harris, JR. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Xiaoyong Fu

IPC分类号： F01D5/18 ,  B23P15/02

CPC分类号： F01D5/081 ,  F01D5/18 ,  F05D2240/81 ,  F05D2260/22141 ,  Y02T50/676

摘要： A platform cooling arrangement in a turbine rotor blade having a platform at an interface between an airfoil and a root, wherein the rotor blade includes an interior cooling passage that extends from a connection at the root to the approximate radial height of the platform, wherein, the interior cooling passage comprises a high-pressure coolant region and a low-pressure coolant region, and wherein a pressure side of the platform comprises a topside extending circumferentially from the airfoil to a pressure side slashface. The platform cooling arrangement may include: a platform cavity formed within the pressure side of the platform, a high-pressure connector that connects the platform cavity to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the platform cavity to the low-pressure coolant region of the interior cooling passage; and a pin bank formed within the platform cavity that includes radial pins.

摘要翻译： 涡轮转子叶片中的平台冷却装置，其具有在翼型件和根部之间的界面处的平台，其中所述转子叶片包括从根部的连接部延伸到所述平台的近似径向高度的内部冷却通道， 内部冷却通道包括高压冷却剂区域和低压冷却剂区域，并且其中平台的压力侧包括从翼面周向延伸到压力侧斜面的顶侧。 平台冷却装置可以包括：形成在平台的压力侧内的平台空腔，将平台空腔连接到内部冷却通道的高压冷却剂区域的高压连接器; 将平台腔连接到内部冷却通道的低压冷却剂区域的低压连接器; 以及形成在所述平台腔内的销排，所述销组包括径向销。

公开(公告)号：US20120156055A1

公开(公告)日：2012-06-21

申请号：US12972835

申请日：2010-12-20

申请人： John Wesley Harris, JR. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Daniel Alan Hynum ,  Melissa Ann Seely ,  Xiaoyong Fu

发明人： John Wesley Harris, JR. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Daniel Alan Hynum ,  Melissa Ann Seely ,  Xiaoyong Fu

IPC分类号： F01D5/18 ,  B23P15/02

CPC分类号： F01D5/187 ,  F01D5/087 ,  F05D2240/81 ,  F05D2250/185 ,  Y02T50/671 ,  Y02T50/676 ,  Y10T29/49341

摘要： A configuration of cooling channels through the interior of a turbine rotor blade, the turbine rotor blade including a platform at an interface between an airfoil and a root. In one embodiment, the configuration of cooling channels includes: an interior cooling passage that is configured to extend from a connection with a coolant source in the root to the interior of the airfoil; a platform cooling channel that traverses at least a portion of the platform; a turndown extension that includes a first section, which comprises a connection with the platform cooling channel, and a second section, which comprises a radially oriented cooling channel; and a connector that extends from a connector opening formed through an outer face of the root to a connection with the interior cooling passage and, therebetween, bisects the second section of the turndown extension.

摘要翻译： 通过涡轮转子叶片的内部的冷却通道的构造，涡轮转子叶片包括在翼型件和根部之间的界面处的平台。 在一个实施例中，冷却通道的构造包括：内部冷却通道，其构造成从与根部中的冷却剂源的连接延伸到翼型件的内部; 平台冷却通道，其横穿所述平台的至少一部分; 包括与所述平台冷却通道的连接的第一部分和包括径向定向的冷却通道的第二部分的调节延伸部; 以及连接器，该连接器从形成为通过根部的外表面的连接器开口延伸到与内部冷却通道的连接，并且在两者之间平分调节延伸部分的第二部分。

公开(公告)号：US08636471B2

公开(公告)日：2014-01-28

申请号：US12972835

申请日：2010-12-20

申请人： John Wesley Harris, Jr. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Daniel Alan Hynum ,  Melissa Ann Seely ,  Xiaoyong Fu

发明人： John Wesley Harris, Jr. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Daniel Alan Hynum ,  Melissa Ann Seely ,  Xiaoyong Fu

IPC分类号： F01D5/18 ,  F01D5/08

CPC分类号： F01D5/187 ,  F01D5/087 ,  F05D2240/81 ,  F05D2250/185 ,  Y02T50/671 ,  Y02T50/676 ,  Y10T29/49341

摘要： A configuration of cooling channels through the interior of a turbine rotor blade, the turbine rotor blade including a platform at an interface between an airfoil and a root. In one embodiment, the configuration of cooling channels includes: an interior cooling passage that is configured to extend from a connection with a coolant source in the root to the interior of the airfoil; a platform cooling channel that traverses at least a portion of the platform; a turndown extension that includes a first section, which comprises a connection with the platform cooling channel, and a second section, which comprises a radially oriented cooling channel; and a connector that extends from a connector opening formed through an outer face of the root to a connection with the interior cooling passage and, therebetween, bisects the second section of the turndown extension.

摘要翻译： 通过涡轮转子叶片的内部的冷却通道的构造，涡轮转子叶片包括在翼型件和根部之间的界面处的平台。 在一个实施例中，冷却通道的构造包括：内部冷却通道，其构造成从与根部中的冷却剂源的连接延伸到翼型件的内部; 平台冷却通道，其横穿所述平台的至少一部分; 包括与所述平台冷却通道的连接的第一部分和包括径向定向的冷却通道的第二部分的调节延伸部; 以及连接器，该连接器从形成为通过根部的外表面的连接器开口延伸到与内部冷却通道的连接，并且在两者之间平分调节延伸部分的第二部分。

公开(公告)号：US08814518B2

公开(公告)日：2014-08-26

申请号：US12915477

申请日：2010-10-29

申请人： John Wesley Harris, Jr. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Xiaoyong Fu

发明人： John Wesley Harris, Jr. ,  Craig Allen Bielek ,  Scott Edmond Ellis ,  Xiaoyong Fu

IPC分类号： F01D5/18

CPC分类号： F01D5/081 ,  F01D5/18 ,  F05D2240/81 ,  F05D2260/22141 ,  Y02T50/676

摘要： A platform cooling arrangement in a turbine rotor blade having a platform at an interface between an airfoil and a root, wherein the rotor blade includes an interior cooling passage that extends from a connection at the root to the approximate radial height of the platform, wherein, the interior cooling passage comprises a high-pressure coolant region and a low-pressure coolant region, and wherein a pressure side of the platform comprises a topside extending circumferentially from the airfoil to a pressure side slashface. The platform cooling arrangement may include: a platform cavity formed within the pressure side of the platform, a high-pressure connector that connects the platform cavity to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the platform cavity to the low-pressure coolant region of the interior cooling passage; and a pin bank formed within the platform cavity that includes radial pins.

摘要翻译： 涡轮转子叶片中的平台冷却装置，其具有在翼型件和根部之间的界面处的平台，其中所述转子叶片包括从根部的连接部延伸到所述平台的近似径向高度的内部冷却通道， 内部冷却通道包括高压冷却剂区域和低压冷却剂区域，并且其中平台的压力侧包括从翼面周向延伸到压力侧斜面的顶侧。 平台冷却装置可以包括：形成在平台的压力侧内的平台空腔，将平台空腔连接到内部冷却通道的高压冷却剂区域的高压连接器; 将平台腔连接到内部冷却通道的低压冷却剂区域的低压连接器; 以及形成在所述平台腔内的销排，所述销组包括径向销。

公开(公告)号：US20120082550A1

公开(公告)日：2012-04-05

申请号：US12895035

申请日：2010-09-30

申请人： John Wesley Harris, JR. ,  Scott Edmond Ellis ,  Xiaoyong Fu ,  Adrian Lional Scott

发明人： John Wesley Harris, JR. ,  Scott Edmond Ellis ,  Xiaoyong Fu ,  Adrian Lional Scott

IPC分类号： F01D5/08 ,  B23P15/04

CPC分类号： F01D5/081 ,  F01D5/186 ,  F05D2240/81 ,  Y02T50/676

摘要： A platform cooling configuration in a turbine rotor blade that includes platform slot formed through at least one of the pressure side slashface and the suction side slashface; a removably-engaged impingement insert that separates the platform into two radially stacked plenums, a first plenum that resides inboard of a second plenum; a high-pressure connector that connects the first plenum to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the second plenum to the low-pressure coolant region of the interior cooling passage.

摘要翻译： 涡轮转子叶片中的平台冷却结构，其包括通过压力侧斜面和吸力侧斜面中的至少一个形成的平台槽; 可拆卸地接合的冲击插入件，其将平台分离成两个径向堆叠的通风室，第一增压室位于第二增压室内; 将第一增压室连接到内部冷却通道的高压冷却剂区域的高压连接器; 将第二增压室连接到内部冷却通道的低压冷却剂区域的低压连接器。

公开(公告)号：US08684664B2

公开(公告)日：2014-04-01

申请号：US12895035

申请日：2010-09-30

申请人： John Wesley Harris, Jr. ,  Scott Edmond Ellis ,  Xiaoyong Fu ,  Adrian Lional Scott

发明人： John Wesley Harris, Jr. ,  Scott Edmond Ellis ,  Xiaoyong Fu ,  Adrian Lional Scott

IPC分类号： F01D5/08

CPC分类号： F01D5/081 ,  F01D5/186 ,  F05D2240/81 ,  Y02T50/676

摘要： A platform cooling configuration in a turbine rotor blade that includes platform slot formed through at least one of the pressure side slashface and the suction side slashface; a removably-engaged impingement insert that separates the platform into two radially stacked plenums, a first plenum that resides inboard of a second plenum; a high-pressure connector that connects the first plenum to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the second plenum to the low-pressure coolant region of the interior cooling passage.

摘要翻译： 涡轮转子叶片中的平台冷却结构，其包括通过压力侧斜面和吸力侧斜面中的至少一个形成的平台槽; 可拆卸地接合的冲击插入件，其将平台分离成两个径向堆叠的通风室，第一增压室位于第二增压室内; 将第一增压室连接到内部冷却通道的高压冷却剂区域的高压连接器; 将第二增压室连接到内部冷却通道的低压冷却剂区域的低压连接器。

公开(公告)号：US08814517B2

公开(公告)日：2014-08-26

申请号：US12894914

申请日：2010-09-30

申请人： Scott Edmond Ellis ,  Xiaoyong Fu

发明人： Scott Edmond Ellis ,  Xiaoyong Fu

IPC分类号： F01D5/18

CPC分类号： F01D5/186 ,  F01D5/081 ,  F05D2240/81 ,  Y02T50/672 ,  Y02T50/676

摘要： In a turbine rotor blade having a platform at an interface between an airfoil and a root, wherein the airfoil and the root include an interior cooling passage formed therein, wherein, in operation, the interior cooling passage comprises at least a high-pressure coolant region and a low-pressure coolant region, platform cooling arrangement that includes: a platform slot extending circumferentially from a mouth formed through the pressure side slashface; a high-pressure connector that connects the platform slot to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the platform slot to the low-pressure coolant region of the interior cooling passage; and a platform cooling cartridge removably engaged within the platform slot, the platform cooling cartridge comprising one or more cartridge cooling channels.

摘要翻译： 在具有在翼型件和根部之间的界面处的平台的涡轮机转子叶片中，其中所述翼型件和根部包括形成在其中的内部冷却通道，其中，在操作中，所述内部冷却通道至少包括高压冷却剂区域 和低压冷却剂区域，平台冷却装置，其包括：从通过压力侧斜面形成的口周向延伸的平台槽; 将所述平台槽与所述内部冷却通道的高压冷却剂区域连接的高压连接器; 将所述平台槽与所述内部冷却通道的低压冷却剂区域连接的低压连接器; 以及可拆卸地接合在所述平台槽内的平台冷却筒，所述平台冷却筒包括一个或多个筒冷却通道。

公开(公告)号：US20120082565A1

公开(公告)日：2012-04-05

申请号：US12894914

申请日：2010-09-30

申请人： Scott Edmond Ellis ,  Xiaoyong Fu

发明人： Scott Edmond Ellis ,  Xiaoyong Fu

IPC分类号： F01D5/18 ,  B23P15/02

CPC分类号： F01D5/186 ,  F01D5/081 ,  F05D2240/81 ,  Y02T50/672 ,  Y02T50/676

摘要： In a turbine rotor blade having a platform at an interface between an airfoil and a root, wherein the airfoil and the root include an interior cooling passage formed therein, wherein, in operation, the interior cooling passage comprises at least a high-pressure coolant region and a low-pressure coolant region, platform cooling arrangement that includes: a platform slot extending circumferentially from a mouth formed through the pressure side slashface; a high-pressure connector that connects the platform slot to the high-pressure coolant region of the interior cooling passage; a low-pressure connector that connects the platform slot to the low-pressure coolant region of the interior cooling passage; and a platform cooling cartridge removably engaged within the platform slot, the platform cooling cartridge comprising one or more cartridge cooling channels.

摘要翻译： 在具有在翼型件和根部之间的界面处的平台的涡轮机转子叶片中，其中所述翼型件和根部包括形成在其中的内部冷却通道，其中，在操作中，所述内部冷却通道至少包括高压冷却剂区域 和低压冷却剂区域，平台冷却装置，其包括：从通过压力侧斜面形成的口周向延伸的平台槽; 将所述平台槽与所述内部冷却通道的高压冷却剂区域连接的高压连接器; 将所述平台槽与所述内部冷却通道的低压冷却剂区域连接的低压连接器; 以及可拆卸地接合在所述平台槽内的平台冷却筒，所述平台冷却筒包括一个或多个筒冷却通道。

公开(公告)号：US08383810B2

公开(公告)日：2013-02-26

申请号：US13323366

申请日：2011-12-12

申请人： Tiruvettipuram K. Thiruvengadam ,  John S. Chiu ,  Xiaoyong Fu ,  Timothy L. McAllister

发明人： Tiruvettipuram K. Thiruvengadam ,  John S. Chiu ,  Xiaoyong Fu ,  Timothy L. McAllister

IPC分类号： C07D205/08 ,  C07H7/02

CPC分类号： C07D205/08 ,  C07H17/02

摘要： A process is provided for preparing azetidinones useful as intermediates in the synthesis of penems and as hypocholesterolemic agents, comprising reacting a β-(substituted-amino)amide, a β-(substituted-amino)acid ester, or a β-(substituted-amino)thiolcarbonic acid ester with a silylating agent and a cyclizing agent selected from the group consisting of alkali metal carboxylates, quaternary ammonium carboxylates, quaternary ammonium hydroxides, quaternary ammonium alkoxides, quaternary ammonium aryloxides and hydrates thereof, or the reaction product of: (i) at least one quaternary ammonium halide and at least one alkali metal carboxylate; or (ii) at least one quaternary ammonium chloride, quaternary ammonium bromide, or quaternary ammonium iodide and at least one alkali metal fluoride, wherein a quaternary ammonium moiety of the cyclizing agent is unsubstituted or substituted by one to four groups independently selected from the group consisting of alkyl, arylalkyl and arylalkyl-alkyl.

摘要翻译： 提供了一种制备氮杂环丁酮的方法，所述氮杂环丁酮可用作半乳聚糖和低胆固醇血症药物的合成中的中间体，包括使（b） - （取代的 - 氨基）酰胺，和（取代的 - 氨基）酸酯， （取代 - 氨基）硫代碳酸酯与甲硅烷基化剂和选自碱金属羧酸盐，季铵羧酸盐，季铵氢氧化物，季铵醇盐，季铵氧化物及其水合物的环化剂或其反应产物 ：（i）至少一种季铵卤化物和至少一种碱金属羧酸盐; 或（ii）至少一种季铵氯化物，季铵溴化物或季铵碘化物和至少一种碱金属氟化物，其中环化剂的季铵部分是未取代的或被一至四个独立地选自 由烷基，芳烷基和芳基烷基 - 烷基组成。

公开(公告)号：US08329905B2

公开(公告)日：2012-12-11

申请号：US12701174

申请日：2010-02-05

申请人： Kelvin H. Yong ,  Ilia A. Zavialov ,  Jianguo Yin ,  Xiaoyong Fu ,  Thiruvettipuram K. Thiruvengadam

发明人： Kelvin H. Yong ,  Ilia A. Zavialov ,  Jianguo Yin ,  Xiaoyong Fu ,  Thiruvettipuram K. Thiruvengadam

IPC分类号： C07F9/40

CPC分类号： C07D405/06 ,  C07F9/58

摘要： This application discloses a novel process for the preparation of phosphonate esters useful as intermediates in the preparation of himbacine analogs, themselves useful as thrombin receptor antagonists. The chemistry taught herein can be exemplified by the following scheme: wherein R9 is selected from alkyl, aryl heteroaryl and arylalkyl groups having 1 to 10 carbon atoms, and R11 is selected independently for each occurrence from alkyl, aryl heteroaryl and arylalkyl groups having 1 to 10 carbon atoms and hydrogen, X2 is Cl, Br, or I; X3 is selected from Cl and Br; and PdLn is a supported palladium metal catalyst or a soluble heterogeneous palladium catalyst. The L-derivatizing reagent is a moiety which converts the alcohol functional group of compound 137D to any leaving group which can be displaced by a triorgano-phosphite phosphonating agent.

摘要翻译： 本申请公开了一种制备膦酸酯的新方法，其可用作制备作为凝血酶受体拮抗剂的替卡宾类似物的中间体。 本文教导的化学实例可以通过以下方案来举例说明：其中R9选自具有1-10个碳原子的烷基，芳基杂芳基和芳基烷基，R11各自独立地选自烷基，芳基杂芳基和具有1至 10个碳原子和氢，X2是Cl，Br或I; X3选自Cl和Br; PdLn是负载型钯金属催化剂或可溶性多相钯催化剂。 L-衍生试剂是将化合物137D的醇官能团转化成可被三有机 - 亚磷酸酯膦酸酯取代的任何离去基团的部分。