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    Compartmentalized device for cell culture, cell processing, and sample dialysis
    1.
    发明申请
    Compartmentalized device for cell culture, cell processing, and sample dialysis 有权
    用于细胞培养，细胞处理和样品透析的分隔装置

    公开(公告)号：US20050101009A1

    公开(公告)日：2005-05-12

    申请号：US10985339

    申请日：2004-11-10

    申请人： John Wilson ,  Dan Welch ,  Alison Robeck ,  Douglas Page

    发明人： John Wilson ,  Dan Welch ,  Alison Robeck ,  Douglas Page

    IPC分类号： C12M1/12 ,  C12M1/24 ,  C12M3/04 ,  C12M3/06

    CPC分类号： C12M27/12 ,  C12M23/08 ,  C12M23/34

    摘要： A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.

    摘要翻译： 具有分离隔室的选择性渗透膜的多功能隔室细胞培养装置相对于传统装置提供许多属性。 它可以配置为在滚动或静置时进行高密度细胞培养，共培养和样品透析。 它也可以配置为在隔室之间连续移动液体。 在其他基于膜的细胞培养和生物处理装置中没有发现的属性的广泛组合包括更多的细胞容量，更多的细胞分泌产物能力，更高的细胞和产物密度，增加的培养基能力，最小化外源生长因子的使用，与标准细胞培养设备的相容性 和方案，增加放大效率，滚动或静止时功能的能力，无需泵的灌注能力，以及更有效的样品透析。