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1.发明申请Materials and Methods for Treatment of Pathological Ocular Vascular Proliferation 审中-公开用于治疗病理性眼血管增生的材料和方法公开(公告)号：US20090192226A1
公开(公告)日：2009-07-30
申请号：US12336814
申请日：2008-12-17
申请人： Josef Neu , Maria B. Grant , Joshua Anthony , Kristin Morris , Eduard Poels , Deborah Schade , Hugh Tucker
发明人： Josef Neu , Maria B. Grant , Joshua Anthony , Kristin Morris , Eduard Poels , Deborah Schade , Hugh Tucker
IPC分类号： A61K31/202 , A61P35/00
CPC分类号： A61K31/198 , A61K31/197 , A61K31/202 , A61K38/05 , A61K2300/00
摘要： The subject invention provides for the administration of docosahexaenoic acid in preventing pathological proliferation of blood vessels. The compositions of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution.
摘要翻译： 本发明提供了二十二碳六烯酸在防止血管病理增生中的应用。 本发明的组合物是特别有利的，因为它们是稳定的，生物可利用的，并且可以配制在水溶液中。
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2.发明申请公开(公告)号：US20070166411A1
公开(公告)日：2007-07-19
申请号：US11637484
申请日：2006-12-11
申请人： Joshua Anthony , Catherine Peterson , Kevin Sims , Deborah Schade , Monjur Hossen , Priscilla Samuel
发明人： Joshua Anthony , Catherine Peterson , Kevin Sims , Deborah Schade , Monjur Hossen , Priscilla Samuel
IPC分类号： A61K36/899 , A61K36/28 , A61K36/31 , A01N37/06 , A61K31/724 , A61K31/7012 , A61K31/22
CPC分类号： A61K31/202 , A23L33/12 , A23L33/40 , A23V2002/00 , A61K2300/00 , A23V2200/30 , A23V2250/1868 , A23V2250/1882
摘要： The present invention relates to a nutritional supplement for administration to children. The supplement comprises a protein component, a carbohydrate component, and a fat or lipid component which further comprises a source of DHA. The supplement has an ω-6:ω3 fatty acid ratio of about 6:1 or less. The present invention also relates to a method of providing nutrition to a pediatric subject comprising administering to the subject a nutritional supplement comprising a protein component; a carbohydrate component; and a fat or lipid component, which further comprises a source of DHA, wherein the composition has an ω-6:ω-3 fatty acid ratio of about 6:1 or less.
摘要翻译： 本发明涉及一种用于给予儿童的营养补充剂。 补充物包含蛋白质组分，碳水化合物组分和进一步包含DHA来源的脂肪或脂质组分。 该补充物具有约6:1或更低的ω-6：ω3脂肪酸比例。 本发明还涉及向儿科受试者提供营养的方法，包括向受试者施用包含蛋白质组分的营养补充剂; 碳水化合物成分; 脂肪或脂质组分，其进一步包含DHA源，其中所述组合物的ω-6：ω-3脂肪酸比例为约6:1或更低。
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3.发明申请Enternal administration of arginine and glutamine for abnormal vascular proliferation 审中-公开精氨酸和谷氨酰胺的异常血管增生的永久管理公开(公告)号：US20060229256A1
公开(公告)日：2006-10-12
申请号：US11392913
申请日：2006-03-29
申请人： Joshua Anthony , Josef Neu , Maria Grant
发明人： Joshua Anthony , Josef Neu , Maria Grant
IPC分类号： A61K38/04 , A61K31/198
摘要： The subject invention provides a method and compositions for preventing and/or treating abnormal vascular proliferation in a human infant where the method involves enterally administering arginine and glutamine to the infant in about equimolar amounts to provide a total amount of arginine and glutamine that is effective to prevent or treat the abnormal vascular proliferation. Arginyl-glutamine dipeptide was shown to be an advantageous form in which to provide the two amino acids.
摘要翻译： 本发明提供了一种用于预防和/或治疗人类婴儿异常血管增生的方法和组合物，其中所述方法涉及以约等摩尔量向婴儿肠内施用精氨酸和谷氨酰胺，以提供总量的精氨酸和谷氨酰胺，其对 预防或治疗异常血管增生。 显示出精氨酰 - 谷氨酰胺二肽是提供两种氨基酸的有利形式。
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4.发明申请Arginyl-glutamine dipeptide for treatment of pathological vascular proliferation 审中-公开用于治疗病理性血管增生的精氨酰 - 谷氨酰胺二肽公开(公告)号：US20050089547A1
公开(公告)日：2005-04-28
申请号：US10950734
申请日：2004-09-27
申请人： Josef Neu , Maria Grant , Joshua Anthony
发明人： Josef Neu , Maria Grant , Joshua Anthony
摘要： The subject invention provides dipeptides useful in preventing pathological proliferation of blood vessels. The dipeptides of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution, and in particular, into infant formulations.
摘要翻译： 本发明提供了可用于预防血管病理增殖的二肽。 本发明的二肽是特别有利的，因为它们是稳定的，生物可利用的，并且可以配制在水溶液中，特别是配制成婴儿制剂。
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公开(公告)号：US20070203237A1
公开(公告)日：2007-08-30
申请号：US11711196
申请日：2007-02-27
申请人： J. Brenna , Kristin Morris , Joshua Anthony , Steven Rumsey
发明人： J. Brenna , Kristin Morris , Joshua Anthony , Steven Rumsey
IPC分类号： A61K31/202 , A61K47/00
CPC分类号： A61K31/202 , A61K2300/00
摘要： The present invention is directed to a novel method for preventing or treating obesity in a subject. The method comprises administration of a therapeutically effective amount of DHA and ARA, alone or in combination with one another, to the subject.
摘要翻译： 本发明涉及一种用于预防或治疗受试者中肥胖症的新方法。 该方法包括将单独或彼此组合的治疗有效量的DHA和ARA给予受试者。
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6.发明申请Enteral Administration Of Arginine-Glutamine Dipeptide To Support Retinal, Intestinal, Or Nervous System Development 审中-公开肠内营养精氨酸 - 谷氨酰胺二肽支持视网膜，肠道或神经系统发育公开(公告)号：US20110086809A1
公开(公告)日：2011-04-14
申请号：US12578922
申请日：2009-10-14
申请人： Joshua Anthony , Kristin Morris , Maria Grant , Joseph Neu
发明人： Joshua Anthony , Kristin Morris , Maria Grant , Joseph Neu
摘要： A method for supporting retinal, intestinal, and/or nervous system development in a neonate is provided. The method involves enterally administering arginine-glutamine dipeptide to a neonate.
摘要翻译： 提供了一种支持新生儿视网膜，肠和/或神经系统发育的方法。 该方法涉及将精氨酸 - 谷氨酰胺二肽肠内施用于新生儿。
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公开(公告)号：US20070203235A1
公开(公告)日：2007-08-30
申请号：US11364619
申请日：2006-02-28
申请人： Francisco Rosales , Joshua Anthony , James Brenna , Andrea Hsieh
发明人： Francisco Rosales , Joshua Anthony , James Brenna , Andrea Hsieh
IPC分类号： A61K31/202
CPC分类号： A61K31/202 , A23L33/12 , A23V2002/00 , A61K45/06 , A61K2300/00 , A23V2250/1868 , A23V2250/1862
摘要： The present invention is directed to a novel method for preventing or treating anemia in a subject. The method comprises administration of a therapeutically effective amount of DHA and ARA to the subject.
摘要翻译： 本发明涉及一种用于预防或治疗受试者中的贫血的新方法。 该方法包括向受试者施用治疗有效量的DHA和ARA。
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8.发明申请Compositions and methods of formulation for enteral formulas containing sialic acid 有权含有唾液酸的肠内配方的组合物和制剂方法公开(公告)号：US20050096295A1
公开(公告)日：2005-05-05
申请号：US10964290
申请日：2004-10-13
CPC分类号： A23C9/1307 , A23C9/20 , A23L33/10 , A23L33/18 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2250/5438 , A23V2250/5424 , A23V2250/1868 , A23V2250/187 , A23V2250/70 , A23V2250/156 , A23V2250/06
摘要： A nutritionally complete infant formula containing sialic acid derived from one or a number of nutritionally appropriate sources is described.
摘要翻译： 描述了一种营养完整的含有唾液酸的婴儿配方，其含有一种或多种营养适宜的来源。
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公开(公告)号：US20090099259A1
公开(公告)日：2009-04-16
申请号：US11712102
申请日：2007-02-28
申请人： Zeina Jouni , Joshua Anthony , Steven C. Rumsey , Deshanie Rai , Kumar Sesha Kothapalli , James T. Brenna
发明人： Zeina Jouni , Joshua Anthony , Steven C. Rumsey , Deshanie Rai , Kumar Sesha Kothapalli , James T. Brenna
CPC分类号： A61K31/202
摘要： The present invention is directed to a novel method for modulating the expression of one or more genes in a subject by administering an amount of DHA and ARA to the subject.
摘要翻译： 本发明涉及通过向受试者施用一定量的DHA和ARA来调节受试者中一种或多种基因的表达的新方法。
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