公开(公告)号：US20060083760A1

公开(公告)日：2006-04-20

申请号：US10672040

申请日：2003-09-26

申请人： Joseph Olijve ,  Jan Bouwstra ,  Frederik Wolf De ,  Marc Werten ,  Hendrik Wisselink ,  Richele Wind ,  Tanja Bosch Van Den ,  Yuzo Toda

发明人： Joseph Olijve ,  Jan Bouwstra ,  Frederik Wolf De ,  Marc Werten ,  Hendrik Wisselink ,  Richele Wind ,  Tanja Bosch Van Den ,  Yuzo Toda

IPC分类号： A61K8/65

CPC分类号： G03C1/005

摘要： The invention provides oil-in-water emulsions comprising recombinant collagen-like polymer in an amount sufficient to act as stabiliser of the emulsion. The polymer is especially a polypeptide which is free of helix structure, has an isoelectric point at least 0.5 pH units removed from the pH of the oil-in-water emulsion. Furthermore, amphiphilic recombinant collagen-like polymers are provided for use in oil-in-water emulsions. The amphiphilic polymers are polar at one end as a result of a relative abundance of polar amino acids, and apolar at the other end as a result of a relative abundance of apolar amino acids.

摘要翻译： 本发明提供了包含足以作为乳液稳定剂的量的重组胶原样聚合物的水包油乳液。 聚合物特别是不含螺旋结构的多肽，具有从水包油乳液的pH去除至少0.5个pH单位的等电点。 此外，提供两亲重组胶原样聚合物用于水包油乳剂中。 由于极性氨基酸的相对丰度，两亲聚合物在一端是极性的，另一端由于非极性氨基酸的相对丰度而非极性。