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公开(公告)号:US20160280783A1
公开(公告)日:2016-09-29
申请号:US15180879
申请日:2016-06-13
申请人: Joy GHOSH , Mark Anthony RUTZ , Kathrin Ulrike TISSOT-DAGUETTE , Igor SPLAWSKI , Michael ROGUSKA
发明人: Joy GHOSH , Mark Anthony RUTZ , Kathrin Ulrike TISSOT-DAGUETTE , Igor SPLAWSKI , Michael ROGUSKA
IPC分类号: C07K16/26 , A61K39/395 , C07K16/22 , A61K45/06
CPC分类号: C07K16/26 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to compositions and methods for the inhibition of EPO. The invention provides antibodies and antigen binding fragments thereof that bind to EPO and are able to inhibit EPO-dependent cell proliferation and/or EPO-dependent cell signaling.
摘要翻译: 本发明涉及抑制EPO的组合物和方法。 本发明提供了结合EPO并能够抑制EPO依赖性细胞增殖和/或EPO依赖性细胞信号传导的抗体及其抗原结合片段。
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公开(公告)号:US20140199306A1
公开(公告)日:2014-07-17
申请号:US14095910
申请日:2013-12-03
申请人: Joy GHOSH , Mark Anthony RUTZ , Katrin Ulrike TISSOT-DAGUETTE , Igor SPLAWSKI , Michael ROGUSKA
发明人: Joy GHOSH , Mark Anthony RUTZ , Katrin Ulrike TISSOT-DAGUETTE , Igor SPLAWSKI , Michael ROGUSKA
IPC分类号: C07K16/26
CPC分类号: C07K16/26 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to compositions and methods for the inhibition of EPO. The invention provides antibodies and antigen binding fragments thereof that bind to EPO and are able to inhibit EPO-dependent cell proliferation and/or EPO-dependent cell signaling.
摘要翻译: 本发明涉及抑制EPO的组合物和方法。 本发明提供了结合EPO并能够抑制EPO依赖性细胞增殖和/或EPO依赖性细胞信号传导的抗体及其抗原结合片段。
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