-
公开(公告)号:US06689906B1
公开(公告)日:2004-02-10
申请号:US10130023
申请日:2002-04-19
IPC分类号: C07C6106
CPC分类号: A61K31/195 , C07C229/28 , C07C2602/18 , C07C2602/20 , C07C2602/22 , C07C2602/24 , C07C2602/28
摘要: The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.
摘要翻译: 本发明是可用于治疗癫痫,微弱发作,神经变性疾病,抑郁症,焦虑症,恐慌症,疼痛,神经病理学障碍,胃肠道疾病如肠易激综合征(IBS)和炎症的新一系列环状氨基酸, 特别是关节炎。 包括含有本发明化合物的药物组合物以及制备化合物的方法和用于制备最终化合物的新中间体。
-
公开(公告)号:US06835751B2
公开(公告)日:2004-12-28
申请号:US10762026
申请日:2004-01-21
IPC分类号: A01N3712
CPC分类号: A61K31/195 , C07C229/28 , C07C2602/18 , C07C2602/20 , C07C2602/22 , C07C2602/24 , C07C2602/28
摘要: The compounds of the instant invention are bicyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropathological disorders, and sleep disorders. Processes for the preparation of the final products and intermediates useful in the process are included. Pharmaceutical compositions containing one or more of the compounds are also included.
-