公开(公告)号：US20230181587A1

公开(公告)日：2023-06-15

申请号：US17997974

申请日：2021-05-07

Applicant: KAGOSHIMA UNIVERSITY ,  OSAKA UNIVERSITY

Inventor： Takashi KURIHARA ,  Ichiro TAKASAKI ,  Hitoshi HASHIMOTO ,  Atsuko HAYATA ,  Yusuke SHINTANI

IPC: A61K31/519 ,  A61K31/4178 ,  A61P25/24 ,  A61P25/22

CPC classification number: A61K31/519 ,  A61K31/4178 ,  A61P25/24 ,  A61P25/22

Abstract: This invention relates to an antidepressant/anxiolytic drug comprising a compound represented by the following formula (I) or (II),




wherein R1 is a hydrogen atom, a C1-6-alkyl group, a C1-6-alkoxy group, a C2-6-alkenyloxy group, a halogen atom, a C1-6-haloalkyl group, a C1-6-haloalkoxy group, or a substituted or unsubstituted phenyl group; R2 is a hydrogen atom, a C1-6-alkyl group, a C1-6-alkoxy group, a C2-6-alkenyloxy group, a halogen atom, a C1-6-haloalkyl group, a C1-6-haloalkoxy group, or a substituted or unsubstituted phenyl group; and R is an indazolyl group substituted with a halogen atom; a substituted or unsubstituted phenyl group; a pyrazolyl group; or a substituted or unsubstituted aralkyl group;

or a salt thereof, or a solvate thereof.