公开(公告)号：US20080081994A1

公开(公告)日：2008-04-03

申请号：US11866000

申请日：2007-10-02

申请人： KANG KIM ,  William Weitzel ,  Jonathan Rubin ,  Congxian Jia ,  Matthew O'Donnell ,  Theodore Kolias

发明人： KANG KIM ,  William Weitzel ,  Jonathan Rubin ,  Congxian Jia ,  Matthew O'Donnell ,  Theodore Kolias

IPC分类号： A61B8/00

CPC分类号： A61B5/0285 ,  A61B8/06 ,  A61B8/08 ,  A61B8/485 ,  G01S7/52036 ,  G01S7/52042

摘要： An optimized elastic modulus reconstruction procedure can estimate the nonlinear elastic properties of vascular wall from intramural strain and pulse wave velocity (PWV) measurements. A noninvasive free-hand ultrasound scanning procedure is used to apply external force, comparable to the force in measuring a subject's blood pressure, to achieve higher strains by equalizing the internal arterial baseline pressure. PWV is estimated at the same location where intramural strain is measured. The reconstructed elastic modulus is optimized and the arterial elastic modulus can be determined and monitored using a simple dual elastic modulus reconstruction procedure.

摘要翻译： 优化的弹性模量重建程序可以从壁内应变和脉搏波速度（PWV）测量中估计血管壁的非线性弹性特性。 使用非侵入性自由手超声扫描程序来施加外力，与测量受试者血压的力相当，以通过平衡内部动脉基线压力来实现更高的应变。 PWV估计在测量壁内应变的相同位置。 重建的弹性模量被优化，并且可以使用简单的双弹性模量重建程序来确定和监测动脉弹性模量。