公开(公告)号：US20130136324A1

公开(公告)日：2013-05-30

申请号：US13683931

申请日：2012-11-21

Applicant: Keio University ,  Nec Corporation

Inventor： Michiie SAKAMOTO ,  Akinori HASHIGUCHI ,  Tokiya ABE ,  Akira SAITO ,  Maki SANO

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G06K9/00147 ,  G06K9/6277 ,  G06T2207/20021 ,  G06T2207/30024 ,  G06T2207/30056

Abstract: A pathological diagnosis assisting apparatus according to the present invention includes an image classification unit configured to classify at least one type of a specific substance, a tissue area extraction unit configured to extract a tissue area in the image of the sample, an image dividing unit configured to divide the tissue area into a plurality of sections, a specific substance occupancy rate calculation unit configured to, calculate an occupancy rate of the at least one type of the specific substance in each of the plurality of sections, and a diagnosis assisting information providing unit configured to determine an intermediate value of the occupancy rate of the specific substance from the calculated occupancy rates of the plurality of sections and to provide the intermediate value as the diagnosis assisting information.

Abstract translation: 根据本发明的病理诊断辅助装置包括：图像分类单元，被配置为对至少一种类型的特定物质进行分类;组织区域提取单元，被配置为提取样本的图像中的组织区域，图像分割单元配置 将所述组织区域分割成多个区段，所述特定物质占有率计算单元被配置为计算所述多个区间中的所述至少一种类型的特定物质的占有率，以及诊断辅助信息提供单元 被配置为根据所计算的多个部分的占用率来确定特定物质的占用率的中间值，并且提供中间值作为诊断辅助信息。

公开(公告)号：US20160232665A1

公开(公告)日：2016-08-11

申请号：US15022032

申请日：2014-08-15

Applicant: NEC CORPORATION ,  KEIO UNIVERSITY

Inventor： Michiie SAKAMOTO ,  Akinori HASHIGUCHI ,  Ken YAMAZAKI ,  Tokiya ABE ,  Akira SAITO ,  Tomoharu KIYUNA

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G06K9/00127 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30096

Abstract: An image acquisition unit (2020) acquires an analysis image. The analysis image is an image in which a plurality of cell nuclei in a lesion of a target person are captured. A feature-value calculation unit (2040) calculates the feature-value relating to the cell nuclei from the analysis image. An evaluation function acquisition unit (2060) acquires an evaluation function from an evaluation function storage unit (10). The evaluation function is a function with which prediction information is calculated based on the feature-value. The prediction information generation unit (2080) generates prediction information relating to a target person based on a feature-value, which has been calculated from an analysis image, and an evaluation function which has been acquired by the evaluation function acquisition unit (2060). The prediction information is information indicating a prediction of a prognosis of a disease of the target person or a prediction of malignancy of a disease of the target person.

Abstract translation: 图像获取单元（2020）获取分析图像。 分析图像是其中捕获目标人物的病变中的多个细胞核的图像。 特征值计算单元（2040）从分析图像计算与细胞核相关的特征值。 评估函数获取单元（2060）从评估函数存储单元（10）获取评估函数。 评估函数是基于特征值计算预测信息的函数。 预测信息生成部（2080）基于从分析图像计算出的特征量和评价函数获取部（2060）获取的评价函数，生成与目标人物有关的预测信息。 预测信息是指示目标人的疾病的预后的预测或目标人的疾病的恶性的预测的信息。

公开(公告)号：US20130136325A1

公开(公告)日：2013-05-30

申请号：US13686768

申请日：2012-11-27

Applicant: KEIO UNIVERSITY ,  NEC CORPORATION

Inventor： Michiie SAKAMOTO ,  Akinori HASHIGUCHI ,  Tokiya ABE ,  Akira SAITO ,  Maki SANO

IPC: G06T7/00

CPC classification number: G06T7/0012 ,  G06K9/00147 ,  G06T2207/10056 ,  G06T2207/20081 ,  G06T2207/30024

Abstract: A pathological diagnosis assisting apparatus according to the present invention provides the diagnosis assisting information for assisting diagnosis of tissue fibrosis from the image of the stained sample, and includes an image reading unit configured to read the image of the stained sample and an image processing unit configured to process the image. The image processing unit includes an image classification unit configured to classify the collagenous fiber and the elastic fiber, a tissue area extraction unit configured to extract a tissue area, an occupancy rate calculation unit configured to calculate the occupancy rates of the collagenous fiber and the elastic fiber in the tissue area, and a diagnosis assisting information providing unit configured to provide the diagnosis assisting information based on the calculated occupancy rates of the collagenous fiber and the elastic fiber.

Abstract translation: 根据本发明的病理诊断辅助装置提供诊断辅助信息，用于从染色样品的图像中辅助诊断组织纤维化，并且包括：图像读取单元，被配置为读取染色样品的图像;以及图像处理单元， 处理图像。 图像处理单元包括被配置为对胶原纤维和弹性纤维进行分类的图像分类单元，构造成提取组织区域的组织区域提取单元，被配置为计算胶原纤维和弹性体的占有率的占有率计算单元 以及诊断辅助信息提供单元，其被配置为基于计算出的胶原纤维和弹性纤维的占有率来提供诊断辅助信息。