公开(公告)号：US20110293470A1

公开(公告)日：2011-12-01

申请号：US13128571

申请日：2009-11-09

申请人： KIRK S. Schanze ,  Motokatsu Ogawa ,  Jonathan R. Sommer ,  David G. Whitten ,  Thomas Corbitt

发明人： KIRK S. Schanze ,  Motokatsu Ogawa ,  Jonathan R. Sommer ,  David G. Whitten ,  Thomas Corbitt

IPC分类号： A01N25/28 ,  A61L2/232 ,  B05D1/36 ,  A01N41/04 ,  A01P1/00

CPC分类号： A01N25/28 ,  A01N25/00 ,  A01N25/10 ,  A01N25/34 ,  A01N43/90 ,  A61L2/23 ,  Y10S977/712 ,  Y10S977/903 ,  Y10T428/2982 ,  A01N41/04 ,  A01N2300/00

摘要： Hollow conjugated polyelectrolyte (HCPE) microcapsules contain at least one conjugated polyelectrolyte and at least one other polyelectrolyte of complementary charge and the microcapsule has a hollow core. The conjugated polyelectrolyte is a polymer with a multiplicity of charged repeating units where a portion of the charged repeating units form a pi-conjugated sequence. The complementary polyelectrolyte is a polymer with a complementary charged repeating unit to the charged repeating units of the conjugated polyelectrolyte. The HCPE microcapsules can be formed by successively coating a sacrificial core with alternating layers of complementary polyelectrolytes, at least one of which is a conjugated polyelectrolyte. The sacrificial core can be removed to form the hollow center of a HCPE microcapsule. The HCPE microcapsules can be contacted with a medium containing microbes where the HCPE microcapsules associate with the microbes and efficiently kill the microbes when irradiated with light or other electromagnetic radiation.

摘要翻译： 中空共轭聚电解质（HCPE）微胶囊含有至少一种共轭聚电解质和至少一种其他互补电荷的聚电解质，微胶囊具有中空芯。 共轭聚电解质是具有多个带电重复单元的聚合物，其中一部分带电重复单元形成π-共轭序列。 互补聚电解质是与共轭聚电解质的带电重复单元具有互补的带电重复单元的聚合物。 HCPE微胶囊可以通过连续地涂覆具有互补聚电解质交替层的牺牲芯形成，其中至少一种是共轭聚电解质。 可以去除牺牲芯以形成HCPE微胶囊的中空中心。 HCPE微胶囊可以与含有微生物的培养基接触，其中HCPE微胶囊与微生物结合，并在用光或其他电磁辐射照射时有效杀死微生物。