公开(公告)号：US20230000369A1

公开(公告)日：2023-01-05

申请号：US17939413

申请日：2022-09-07

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Shaoxiong SUN ,  Wouter Herman PEETERS ,  Rick BEZEMER

IPC: A61B5/021 ,  A61B5/00

Abstract: The present invention relates to a device, system and method for determining pulse pressure variation of a subject. To enable more reliably determining pulse pressure variation of a subject the device comprises a signal input (11) configured to obtain an input signal representing a hemodynamic signal of the subject, a processor (12) configured to process the input signal and compute a pulse pressure variation and a signal output (13) configured to output the computed pulse pressure variation. The pulse pressure variation is computed by deriving a pulse height signal from the input signal, deriving a pulse height baseline and a de-trended pulse height signal from the pulse height signal as the ratio between the difference between extrema of the de-trended pulse height signal and the respective value of the pulse height baseline signal, and computing the pulse pressure variation from the de-trended pulse height signal and the pulse height baseline.

公开(公告)号：US20190336014A1

公开(公告)日：2019-11-07

申请号：US16475394

申请日：2018-01-02

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Wouter Herman PEETERS ,  Mark Peter Paul KLEIJNEN ,  Gerardus Johannes Nicolaas DOODEMAN ,  Rick BEZEMER ,  Jacobus Josephus LEIJSSEN ,  Ronny Hubertus Johannes GROSFELD

IPC: A61B5/0265 ,  A61B5/00

Abstract: The invention provides a magnetic inductive sensing system for sensing electromagnetic signals emitted from a body in response to electromagnetic excitation signals applied to the body. The electromagnetic signals are generated and sensed by the same loop resonator which comprises a single-turn loop antenna and a tuning capacitor. The loop antenna of the resonator and a signal generation means for exciting the resonator to generate excitation signals are together configured so as to optimize the value of a ratio between the radial frequency of the generated electromagnetic excitation signals and a reference frequency of the antenna, where the reference frequency is the frequency for which one wavelength of the generated excitation signals (waves) matches the circumferential length of the antenna. This ratio, which corresponds to a normalized radial frequency of the generated excitation signals, is maintained between a value of 0.025 and 0.50.

公开(公告)号：US20170202493A1

公开(公告)日：2017-07-20

申请号：US15312841

申请日：2015-05-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Rick BEZEMER

IPC: A61B5/145 ,  A61B5/0295

Abstract: The present invention relates to a device and method for noninvasively determining the hematocrit value of a subject. The device comprises a light source (22, 23) for emitting light onto a skin area of the subject, said light comprising first light at a first wavelength in a first wavelength range between 500 and 1000 nm and second light at a second wavelength in a second wavelength range between 1000 and 2000 nm, a reflection detector (24) for detecting light reflected from said skin area of the subject in response to light illumination by said light source, a transmission detector (25) for detecting light transmitted through said skin area of the subject in response to light illumination by said light source, a processing unit (31) for deriving plethysmography, PPG, signals for said first and second wavelengths from the light detected by said reflection detector (24) and said transmission detector (25), and an analysis unit (32) for determining the hematocrit value of the subject from said PPG signals.

公开(公告)号：US20210321898A1

公开(公告)日：2021-10-21

申请号：US17273361

申请日：2019-08-28

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Wouter Herman PEETERS ,  Jacobus Josephus LEIJSSEN ,  Gerardus Johannes Nicolaas DOODEMAN ,  Rick BEZEMER ,  Mark Peter Paul KLEIJNEN ,  Ronny Hubertus Johannes GROSFELD

IPC: A61B5/05 ,  A61B5/00

Abstract: An inductive sensing device comprises first (16) and second (24) loops, the first loop (16) being coupled with a capacitor to form a resonator circuit (20), and the resonator circuit and second loop being coupled via an active buffering component (28). The active buffering component provides voltage to current amplification, and an output of the buffering component drives a current in the second loop. Conductive lines forming each of the first and second loop parts are radially spaced apart.

公开(公告)号：US20210220630A1

公开(公告)日：2021-07-22

申请号：US17055027

申请日：2019-05-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Igor Wilhelmus Franciscus PAULUSSEN ,  Rick BEZEMER

IPC: A61M35/00 ,  A61B5/00

Abstract: A medical device (10) configured for attachment to skin of a patient includes a vital sign sensor or drug delivery patch (14); and a plurality of suction cells (12) arranged around a periphery of the vital sign sensor or drug delivery patch.

公开(公告)号：US20160143557A1

公开(公告)日：2016-05-26

申请号：US14935727

申请日：2015-11-09

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria KAHLMAN ,  Rick BEZEMER

IPC: A61B5/05 ,  A61B5/00

Abstract: There is provided a measurement apparatus for estimating a value of a physiological characteristic of a subject. The apparatus comprises a radio-frequency (RF) power generating apparatus, a detector, and a controller in communication with the RF power generating apparatus. The RF power generating apparatus comprises a transmit antenna for emitting RF radiation; an RF signal generator; and a transmission line connecting the RF signal generator to the transmit antenna. The detector is arranged to measure the variation of at least one parameter correlated with attenuation of the emitted RF radiation, during the measurement period. The controller is arranged to: cause the RF power generating apparatus to emit RF radiation during a measurement period; receive measurements of the variation of the at least one parameter from the detector; and calculate a value of a physiological characteristic of a subject based on the received measurements.

Abstract translation: 提供了一种用于估计对象的生理特征的值的测量装置。 该装置包括与RF发电装置通信的射频（RF）发电装置，检测器和控制器。 RF发电装置包括用于发射RF辐射的发射天线; 射频信号发生器; 以及将RF信号发生器连接到发射天线的传输线。 检测器被布置成在测量期间测量与发射的RF辐射的衰减相关的至少一个参数的变化。 所述控制器被配置为：使RF发射装置在测量期间发射RF辐射; 从所述检测器接收所述至少一个参数的变化的测量值; 并基于所接收的测量值计算被检体的生理特性的值。

公开(公告)号：US20220071502A1

公开(公告)日：2022-03-10

申请号：US17416074

申请日：2019-12-13

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Wouter Herman PEETERS ,  Mark Peter Paul KLEIJNEN ,  Tim Patrick STEUNEBRINK ,  Gerardus Johannes Nicolaas DOODEMAN ,  Rick BEZEMER ,  Carlijn Andrea VERNOOIJ ,  Ercan Ferit GIGI

IPC: A61B5/05

Abstract: An inductive sensing system (8) is adapted to apply electromagnetic excitation signals into a body, the system comprising a resonator circuit (10) incorporating a loop antenna (12). The system senses signals returned back from the body with the same antenna, based on variation in electrical characteristics of the resonator circuit. The system is configured for separating signals received from different physiological sources within the body. This is performed based on detecting in the resonator circuit electrical characteristics indicative of both a real and an imaginary part of an additional inductance component added to the antenna by received electromagnetic signals. The separating the signals from different physiological sources is based on relative magnitudes of said detected real and imaginary inductance components added to the resonator circuit by the returned signals.

公开(公告)号：US20210100532A1

公开(公告)日：2021-04-08

申请号：US16500145

申请日：2018-03-29

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Franciscus Hendrikus VAN HEESCH ,  Igor Wilhelmus Franciscus PAULUSSEN ,  Nico Maris Adriaan DE WILD ,  Katia DONATO ,  Christianus Martinus VAN HEESCH ,  Rick BEZEMER

IPC: A61B8/00 ,  A61B8/08 ,  A61B8/14 ,  G16H40/67 ,  G16H50/30

Abstract: A wearable bladder monitoring device is disclosed (1) comprising securing means (27, 29) for securing the device to a subject's (40) body; a phased array (11) of ultrasound transducers (10) having configurable output frequencies; a configurable phased array controller (13) adapted to control the phased array to direct ultrasound beams (30, 30′, 30″) into the subject's body under a plurality of discrete beam angles and to collect echo signals (31, 31′, 31″) of said ultrasound beams, wherein the phased array controller (13) is adapted to direct a set of ultrasound beams (30, 30′, 30″) into the subject's body for at least a subset of said discrete beam angles in response to a configuration instruction defining the respective output frequencies of the ultrasound beams in said set; and a device communication module (21) for communicating data pertaining to said echo signals to a remote device (5) to facilitate the remote processing of said data and to receive said configuration instruction from the remote device. Also disclosed is a wearable bladder monitoring system adapted to generate such a configuration instruction for the estimation of the degree of turbidity of urine contained in the monitored bladder with the wearable bladder monitoring device, as well as a computer-implemented method and computer program product for facilitating such urine turbidity estimation.

公开(公告)号：US20210085280A1

公开(公告)日：2021-03-25

申请号：US16967555

申请日：2019-02-05

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Franciscus Hendrikus VAN HEESCH ,  Nico Maris Adriaan DE WILD ,  Rick BEZEMER ,  Igor Wilhelmus Franciscus PAULUSSEN

IPC: A61B8/06 ,  A61B8/08

Abstract: A system for monitoring blood distribution in a subject, the system comprising a processor(38) responsive to Doppler ultrasound data representing arterial blood flow in at least two different locations of the subject, such as the neck and the arm, to obtain velocity (C, B1, B2, B3) or volumetric flow rate at each location, to monitor changes in a predetermined function of the blood flows, and to provide an output indicative of the monitored changes which may result from blood volume centralization. This can indicate the onset of hypovolemia or hypervolemia.

公开(公告)号：US20200367861A1

公开(公告)日：2020-11-26

申请号：US16767626

申请日：2018-11-30

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Nico Maris Adriaan DE WILD ,  Igor Wilhelmus Franciscus PAULUSSEN ,  Rick BEZEMER ,  Sabina MANZARI ,  Denny MATHEW ,  Franciscus Hendrikus VAN HEESCH ,  Christianus Martinus VAN HEESCH ,  Ronaldus Maria AARTS

IPC: A61B8/00 ,  A61B8/12 ,  A61B8/08 ,  A61B8/06

Abstract: Disclosed is a patient monitor control unit (10) comprising a processor arrangement (11, 13) adapted to receive a series of ultrasound measurements received from a sensor (30) comprising at least one configurable ultrasound transducer; process said series of ultrasound measurements to obtain haemodynamic data of a patient coupled to the sensor; control a patient monitor (20) to display the obtained haemodynamic data; evaluate the obtained haemodynamic data to detect a variance in said data; and generate a reconfiguration signal for the at least one configurable ultrasound transducer, wherein the timing of said generation is a function of said evaluation. Also disclosed are a patient monitoring system, a method of operating a patient monitor control unit and a computer program product for implementing such a method.