公开(公告)号：US20220403395A1

公开(公告)日：2022-12-22

申请号：US17851500

申请日：2022-06-28

Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTE

Inventor： Rae Kwon KIM ,  In Gyu Kim ,  Yeon Jee Kahm

IPC: C12N15/113 ,  A61P35/00 ,  A61P11/00 ,  A61P25/00 ,  G01N33/50 ,  A61P35/04

Abstract: The present invention relates to a composition for inhibiting the growth of cancer stem cells, and a use thereof. A WDR34 inhibitor of the present invention inhibits the conversion of cancer cells into cancer stem cells and exhibits activity of inhibiting self-renewal, invasion, and migration of cancer stem cells, and thus can be effectively used as a cancer cell growth or metastasis inhibitor or a cancer stem cell growth inhibitor.