公开(公告)号：US12016936B2

公开(公告)日：2024-06-25

申请号：US17262503

申请日：2019-07-24

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Ki-Yuk Chang ,  Chan-Woo Kim ,  Kwan-Soo Hong ,  Hyun-Seung Lee ,  Hyun-Min Kim

IPC: A61K51/10

CPC classification number: A61K51/1027

Abstract: The present invention relates to a neovascular-targeting contrast medium composition and a method for preparing same. The neovascular-targeting contrast medium composition according to the present invention exhibits high binding force to neovascularization-associated αvβ3 integrin, excellent tissue permeability and biostability, enables simple measurement in vitro, in vivo, or ex vivo, and thus is effective in the detection of neovascularization and in diagnosing diseases associated therewith, and therefore may be usefully employed in the relevant industries.