公开(公告)号：US20130261015A1

公开(公告)日：2013-10-03

申请号：US13850872

申请日：2013-03-26

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： Yeong Hee AHN ,  Jong Shin YOO ,  Park Min SHIN

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N33/57438

Abstract: A method for diagnosing cancer using information on aberrant glycosylation of glycoproteins, which is related with cancer progression. More particularly, the present invention relates to a peptide marker for cancer diagnosis and a method for diagnosing cancer using the peptide marker, wherein glycoproteins aberrantly glycosylated due to cancer incidence and progression is isolated using lectin; and marker peptides generated by hydrolysis or the glycoproteins isolated by the lectin is selected and quantified.

Abstract translation: 使用与癌症进展相关的糖蛋白异常糖基化的信息诊断癌症的方法。 更具体地，本发明涉及用于癌症诊断的肽标记物和使用肽标记物诊断癌症的方法，其中使用凝集素分离由于癌症发生和进展而异常糖基化的糖蛋白; 选择并定量通过水解产生的标记肽或由凝集素分离的糖蛋白。