公开(公告)号：US20190127434A1

公开(公告)日：2019-05-02

申请号：US15553191

申请日：2016-06-21

Applicant: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY

Inventor： Woo-Jong LEE ,  Sung-Gun KIM ,  Dong-Mok LEE ,  Hee-Kyung AN ,  Chi-Min CHOI

IPC: C07K14/705 ,  C07K14/47 ,  C07K19/00 ,  C12N15/62

Abstract: The present disclosure relates to a method for producing a TLR5 agonist protein. According to the present disclosure, the TLR5 agonist protein can be easily separated and purified after biotechnological production. In particular, the fusion partner used for separation and purification is effectively removed so as to minimize the possibility of inhibiting binding to TLR5 and inducing an immune response by the fusion partner.