公开(公告)号：US20180104219A1

公开(公告)日：2018-04-19

申请号：US15784356

申请日：2017-10-16

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Key-Sun KIM ,  Seo-Yeon YOON

IPC: A61K31/4168 ,  A61K31/4174 ,  A61K31/433

CPC classification number: A61K31/4168 ,  A61K31/4174 ,  A61K31/433 ,  A61K45/06 ,  A61K2300/00

Abstract: Provided are a pharmaceutical composition including: an alpha 2 (α2)-adrenoceptor agonist; a regulator of G-protein signaling (RGS) inhibitor, an endocytosis inhibitor, or a combination thereof; and a pharmaceutically acceptable salt, and a method of relieving pain of a subject, the method including administering the pharmaceutical composition to a subject.

公开(公告)号：US20190022067A1

公开(公告)日：2019-01-24

申请号：US16138360

申请日：2018-09-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Key-Sun KIM ,  Seo-Yeon YOON

IPC: A61K31/4168 ,  A61K31/4174 ,  A61K31/433

CPC classification number: A61K31/4168 ,  A61K31/4174 ,  A61K31/433 ,  A61K45/06 ,  A61K2300/00

Abstract: Provided are a pharmaceutical composition including: an alpha 2 (α2)-adrenoceptor agonist; a regulator of G-protein signaling (RGS) inhibitor, an endocytosis inhibitor, or a combination thereof; and a pharmaceutically acceptable salt, and a method of relieving pain of a subject, the method including administering the pharmaceutical composition to a subject.