公开(公告)号：US12060352B2

公开(公告)日：2024-08-13

申请号：US17706628

申请日：2022-03-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Seo Jung Han ,  Sang Hee Lee ,  Hee Jin Jeong ,  Hye Lim Lee ,  Chan Sun Park ,  Sung Joon Kim

IPC: A61K31/519 ,  C07D471/04 ,  C07D487/04

CPC classification number: C07D471/04 ,  C07D487/04

Abstract: The disclosure provides substituted pyrrolo[2,3-d]pyrimidine compounds of Chemical Formula 1 and compositions and uses thereof, wherein R1-R7, X, Y, Cy, m and n are defined in the disclosure. The compounds are useful for inhibiting ENPP1, activating the STING pathway, and treating cancer.